SIRPγ-CD47 Interaction Positively Regulates the Activation of Human T Cells in Situation of Chronic Stimulation

A numerous number of positive and negative signals via various molecules modulate T-cell activation. Within the various transmembrane proteins, SIRPγ is of interest since it is not expressed in rodents. SIRPγ interaction with CD47 is reevaluated in this study. Indeed, we show that the anti-SIRPγ mAb...

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Autores principales: Safa Dehmani, Véronique Nerrière-Daguin, Mélanie Néel, Nathan Elain-Duret, Jean-Marie Heslan, Lyssia Belarif, Caroline Mary, Virginie Thepenier, Kevin Biteau, Nicolas Poirier, Gilles Blancho, Fabienne Haspot
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/e739c9f323054f98b7a63928ad4cb2fa
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