COMPLEX EFFECTS OF SALMOZAN MEDICINE AND PROBIOТIC BACTERIA OF LACTOBACILLUS GENUS ON NATURAL RESISTANCE AND ADAPTIVE IMMUNIТY OF EXPERIMENTAL ANIМALS

Results of study of immunoprotective properties of medicine Salmozan and its combined effect with probiotic bacteria of genus Lactobacillus оп natural resistance and parameters of adaptive immunity of experimental animals аге presented. Salmozan stimulates production of IL-1α, IL-12, TNFα in periton...

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Autores principales: Т. N. Nikolaeva, Е. А. Grigorjeva, V. V. Kozlov, А. V. Pronin
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Lenguaje:RU
Publicado: SPb RAACI 2014
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spelling oai:doaj.org-article:e74381307932481585fa47089af502642021-11-18T08:03:37ZCOMPLEX EFFECTS OF SALMOZAN MEDICINE AND PROBIOТIC BACTERIA OF LACTOBACILLUS GENUS ON NATURAL RESISTANCE AND ADAPTIVE IMMUNIТY OF EXPERIMENTAL ANIМALS1563-06252313-741X10.15789/1563-0625-2010-1-2-81-86https://doaj.org/article/e74381307932481585fa47089af502642014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/48https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XResults of study of immunoprotective properties of medicine Salmozan and its combined effect with probiotic bacteria of genus Lactobacillus оп natural resistance and parameters of adaptive immunity of experimental animals аге presented. Salmozan stimulates production of IL-1α, IL-12, TNFα in peritoneal macrophages, production of MIF in реуеr patch and spleen cells and, thus, activates Th1 cells and cytotoxic T cells. Bacteria of Lactobacillus genus enhance modulating effects of Salmozan оn cellular immune reactions. Results of the experiments carried out provide the basis for conclusion abont stimulation of anti-infection and anticancer immunity bу Salmozan which саn bе used fог immunoprophylaxis and соrrеction of cellular immune reactions bу means of probiotic therapy.Т. N. NikolaevaЕ. А. GrigorjevaV. V. KozlovА. V. ProninSPb RAACIarticleimmunomodulationlactobacillicell-mediated immune responseImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 12, Iss 1-2, Pp 81-86 (2014)
institution DOAJ
collection DOAJ
language RU
topic immunomodulation
lactobacilli
cell-mediated immune response
Immunologic diseases. Allergy
RC581-607
spellingShingle immunomodulation
lactobacilli
cell-mediated immune response
Immunologic diseases. Allergy
RC581-607
Т. N. Nikolaeva
Е. А. Grigorjeva
V. V. Kozlov
А. V. Pronin
COMPLEX EFFECTS OF SALMOZAN MEDICINE AND PROBIOТIC BACTERIA OF LACTOBACILLUS GENUS ON NATURAL RESISTANCE AND ADAPTIVE IMMUNIТY OF EXPERIMENTAL ANIМALS
description Results of study of immunoprotective properties of medicine Salmozan and its combined effect with probiotic bacteria of genus Lactobacillus оп natural resistance and parameters of adaptive immunity of experimental animals аге presented. Salmozan stimulates production of IL-1α, IL-12, TNFα in peritoneal macrophages, production of MIF in реуеr patch and spleen cells and, thus, activates Th1 cells and cytotoxic T cells. Bacteria of Lactobacillus genus enhance modulating effects of Salmozan оn cellular immune reactions. Results of the experiments carried out provide the basis for conclusion abont stimulation of anti-infection and anticancer immunity bу Salmozan which саn bе used fог immunoprophylaxis and соrrеction of cellular immune reactions bу means of probiotic therapy.
format article
author Т. N. Nikolaeva
Е. А. Grigorjeva
V. V. Kozlov
А. V. Pronin
author_facet Т. N. Nikolaeva
Е. А. Grigorjeva
V. V. Kozlov
А. V. Pronin
author_sort Т. N. Nikolaeva
title COMPLEX EFFECTS OF SALMOZAN MEDICINE AND PROBIOТIC BACTERIA OF LACTOBACILLUS GENUS ON NATURAL RESISTANCE AND ADAPTIVE IMMUNIТY OF EXPERIMENTAL ANIМALS
title_short COMPLEX EFFECTS OF SALMOZAN MEDICINE AND PROBIOТIC BACTERIA OF LACTOBACILLUS GENUS ON NATURAL RESISTANCE AND ADAPTIVE IMMUNIТY OF EXPERIMENTAL ANIМALS
title_full COMPLEX EFFECTS OF SALMOZAN MEDICINE AND PROBIOТIC BACTERIA OF LACTOBACILLUS GENUS ON NATURAL RESISTANCE AND ADAPTIVE IMMUNIТY OF EXPERIMENTAL ANIМALS
title_fullStr COMPLEX EFFECTS OF SALMOZAN MEDICINE AND PROBIOТIC BACTERIA OF LACTOBACILLUS GENUS ON NATURAL RESISTANCE AND ADAPTIVE IMMUNIТY OF EXPERIMENTAL ANIМALS
title_full_unstemmed COMPLEX EFFECTS OF SALMOZAN MEDICINE AND PROBIOТIC BACTERIA OF LACTOBACILLUS GENUS ON NATURAL RESISTANCE AND ADAPTIVE IMMUNIТY OF EXPERIMENTAL ANIМALS
title_sort complex effects of salmozan medicine and probioтic bacteria of lactobacillus genus on natural resistance and adaptive immuniтy of experimental aniмals
publisher SPb RAACI
publishDate 2014
url https://doaj.org/article/e74381307932481585fa47089af50264
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