COMPLEX EFFECTS OF SALMOZAN MEDICINE AND PROBIOТIC BACTERIA OF LACTOBACILLUS GENUS ON NATURAL RESISTANCE AND ADAPTIVE IMMUNIТY OF EXPERIMENTAL ANIМALS
Results of study of immunoprotective properties of medicine Salmozan and its combined effect with probiotic bacteria of genus Lactobacillus оп natural resistance and parameters of adaptive immunity of experimental animals аге presented. Salmozan stimulates production of IL-1α, IL-12, TNFα in periton...
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oai:doaj.org-article:e74381307932481585fa47089af502642021-11-18T08:03:37ZCOMPLEX EFFECTS OF SALMOZAN MEDICINE AND PROBIOТIC BACTERIA OF LACTOBACILLUS GENUS ON NATURAL RESISTANCE AND ADAPTIVE IMMUNIТY OF EXPERIMENTAL ANIМALS1563-06252313-741X10.15789/1563-0625-2010-1-2-81-86https://doaj.org/article/e74381307932481585fa47089af502642014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/48https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XResults of study of immunoprotective properties of medicine Salmozan and its combined effect with probiotic bacteria of genus Lactobacillus оп natural resistance and parameters of adaptive immunity of experimental animals аге presented. Salmozan stimulates production of IL-1α, IL-12, TNFα in peritoneal macrophages, production of MIF in реуеr patch and spleen cells and, thus, activates Th1 cells and cytotoxic T cells. Bacteria of Lactobacillus genus enhance modulating effects of Salmozan оn cellular immune reactions. Results of the experiments carried out provide the basis for conclusion abont stimulation of anti-infection and anticancer immunity bу Salmozan which саn bе used fог immunoprophylaxis and соrrеction of cellular immune reactions bу means of probiotic therapy.Т. N. NikolaevaЕ. А. GrigorjevaV. V. KozlovА. V. ProninSPb RAACIarticleimmunomodulationlactobacillicell-mediated immune responseImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 12, Iss 1-2, Pp 81-86 (2014) |
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DOAJ |
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DOAJ |
language |
RU |
topic |
immunomodulation lactobacilli cell-mediated immune response Immunologic diseases. Allergy RC581-607 |
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immunomodulation lactobacilli cell-mediated immune response Immunologic diseases. Allergy RC581-607 Т. N. Nikolaeva Е. А. Grigorjeva V. V. Kozlov А. V. Pronin COMPLEX EFFECTS OF SALMOZAN MEDICINE AND PROBIOТIC BACTERIA OF LACTOBACILLUS GENUS ON NATURAL RESISTANCE AND ADAPTIVE IMMUNIТY OF EXPERIMENTAL ANIМALS |
description |
Results of study of immunoprotective properties of medicine Salmozan and its combined effect with probiotic bacteria of genus Lactobacillus оп natural resistance and parameters of adaptive immunity of experimental animals аге presented. Salmozan stimulates production of IL-1α, IL-12, TNFα in peritoneal macrophages, production of MIF in реуеr patch and spleen cells and, thus, activates Th1 cells and cytotoxic T cells. Bacteria of Lactobacillus genus enhance modulating effects of Salmozan оn cellular immune reactions. Results of the experiments carried out provide the basis for conclusion abont stimulation of anti-infection and anticancer immunity bу Salmozan which саn bе used fог immunoprophylaxis and соrrеction of cellular immune reactions bу means of probiotic therapy. |
format |
article |
author |
Т. N. Nikolaeva Е. А. Grigorjeva V. V. Kozlov А. V. Pronin |
author_facet |
Т. N. Nikolaeva Е. А. Grigorjeva V. V. Kozlov А. V. Pronin |
author_sort |
Т. N. Nikolaeva |
title |
COMPLEX EFFECTS OF SALMOZAN MEDICINE AND PROBIOТIC BACTERIA OF LACTOBACILLUS GENUS ON NATURAL RESISTANCE AND ADAPTIVE IMMUNIТY OF EXPERIMENTAL ANIМALS |
title_short |
COMPLEX EFFECTS OF SALMOZAN MEDICINE AND PROBIOТIC BACTERIA OF LACTOBACILLUS GENUS ON NATURAL RESISTANCE AND ADAPTIVE IMMUNIТY OF EXPERIMENTAL ANIМALS |
title_full |
COMPLEX EFFECTS OF SALMOZAN MEDICINE AND PROBIOТIC BACTERIA OF LACTOBACILLUS GENUS ON NATURAL RESISTANCE AND ADAPTIVE IMMUNIТY OF EXPERIMENTAL ANIМALS |
title_fullStr |
COMPLEX EFFECTS OF SALMOZAN MEDICINE AND PROBIOТIC BACTERIA OF LACTOBACILLUS GENUS ON NATURAL RESISTANCE AND ADAPTIVE IMMUNIТY OF EXPERIMENTAL ANIМALS |
title_full_unstemmed |
COMPLEX EFFECTS OF SALMOZAN MEDICINE AND PROBIOТIC BACTERIA OF LACTOBACILLUS GENUS ON NATURAL RESISTANCE AND ADAPTIVE IMMUNIТY OF EXPERIMENTAL ANIМALS |
title_sort |
complex effects of salmozan medicine and probioтic bacteria of lactobacillus genus on natural resistance and adaptive immuniтy of experimental aniмals |
publisher |
SPb RAACI |
publishDate |
2014 |
url |
https://doaj.org/article/e74381307932481585fa47089af50264 |
work_keys_str_mv |
AT tnnikolaeva complexeffectsofsalmozanmedicineandprobioticbacteriaoflactobacillusgenusonnaturalresistanceandadaptiveimmunityofexperimentalanimals AT eagrigorjeva complexeffectsofsalmozanmedicineandprobioticbacteriaoflactobacillusgenusonnaturalresistanceandadaptiveimmunityofexperimentalanimals AT vvkozlov complexeffectsofsalmozanmedicineandprobioticbacteriaoflactobacillusgenusonnaturalresistanceandadaptiveimmunityofexperimentalanimals AT avpronin complexeffectsofsalmozanmedicineandprobioticbacteriaoflactobacillusgenusonnaturalresistanceandadaptiveimmunityofexperimentalanimals |
_version_ |
1718422577300373504 |