Conjunctival extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue in the fornix: do not overlook conjunctival lymphomas

Masayuki Hata,1 Kazuaki Miyamoto,1 Ken Ogino,1 Shinji Sumiyoshi,2 Nagahisa Yoshimura11Department of Ophthalmology and Visual Sciences, 2Department of Diagnostic Pathology, Kyoto University Graduate School of Medicine, Sakyo, Kyoto, JapanBackground: Here we report three cases of conjunctival lymphoma...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Hata M, Miyamoto K, Ogino K, Sumiyoshi S, Yoshimura N
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/e74b1ee2f3f44ac4833f552870a13a31
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:e74b1ee2f3f44ac4833f552870a13a31
record_format	dspace
spelling	oai:doaj.org-article:e74b1ee2f3f44ac4833f552870a13a312021-12-02T05:10:11ZConjunctival extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue in the fornix: do not overlook conjunctival lymphomas1177-54671177-5483https://doaj.org/article/e74b1ee2f3f44ac4833f552870a13a312013-03-01T00:00:00Zhttp://www.dovepress.com/conjunctival-extranodal-marginal-zone-lymphoma-of-mucosa-associated-ly-a12622https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Masayuki Hata,1 Kazuaki Miyamoto,1 Ken Ogino,1 Shinji Sumiyoshi,2 Nagahisa Yoshimura11Department of Ophthalmology and Visual Sciences, 2Department of Diagnostic Pathology, Kyoto University Graduate School of Medicine, Sakyo, Kyoto, JapanBackground: Here we report three cases of conjunctival lymphoma that were initially unnotified or misdiagnosed as other ocular diseases because of the small tumor size, peripheral tumor location (the tumor was hidden in the fornix), and nonspecific symptoms.Methods: Three patients diagnosed with conjunctivitis or nasolacrimal duct obstruction were referred to our clinic because they were unresponsive to standard medical treatments. Routine anterior segment examination did not reveal any lesions, but further careful examination with a strong eyelid draw revealed minimally elevated tumors in the peripheral fornix under the lid. Excisional biopsies were performed.Results: Histopathologic and immunohistologic examinations indicated the presence of extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma). All patients underwent additional radiation therapy. There was no evidence of recurrence in any patient during the follow-up period.Conclusion: Detection of conjunctival lymphoma can be challenging. If no apparent lesion is present and the patient has nonspecific symptoms, the inner surface of the eyelid should be carefully examined. Elaborate eyelid eversion, with eyeball movement, should be performed to avoid misdiagnosing or overlooking peripheral conjunctival lymphomas.Keywords: MALT lymphoma, conjunctival lymphoma, misdiagnosis, fornixHata MMiyamoto KOgino KSumiyoshi SYoshimura NDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2013, Iss default, Pp 663-666 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Hata M Miyamoto K Ogino K Sumiyoshi S Yoshimura N Conjunctival extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue in the fornix: do not overlook conjunctival lymphomas
description	Masayuki Hata,1 Kazuaki Miyamoto,1 Ken Ogino,1 Shinji Sumiyoshi,2 Nagahisa Yoshimura11Department of Ophthalmology and Visual Sciences, 2Department of Diagnostic Pathology, Kyoto University Graduate School of Medicine, Sakyo, Kyoto, JapanBackground: Here we report three cases of conjunctival lymphoma that were initially unnotified or misdiagnosed as other ocular diseases because of the small tumor size, peripheral tumor location (the tumor was hidden in the fornix), and nonspecific symptoms.Methods: Three patients diagnosed with conjunctivitis or nasolacrimal duct obstruction were referred to our clinic because they were unresponsive to standard medical treatments. Routine anterior segment examination did not reveal any lesions, but further careful examination with a strong eyelid draw revealed minimally elevated tumors in the peripheral fornix under the lid. Excisional biopsies were performed.Results: Histopathologic and immunohistologic examinations indicated the presence of extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma). All patients underwent additional radiation therapy. There was no evidence of recurrence in any patient during the follow-up period.Conclusion: Detection of conjunctival lymphoma can be challenging. If no apparent lesion is present and the patient has nonspecific symptoms, the inner surface of the eyelid should be carefully examined. Elaborate eyelid eversion, with eyeball movement, should be performed to avoid misdiagnosing or overlooking peripheral conjunctival lymphomas.Keywords: MALT lymphoma, conjunctival lymphoma, misdiagnosis, fornix
format	article
author	Hata M Miyamoto K Ogino K Sumiyoshi S Yoshimura N
author_facet	Hata M Miyamoto K Ogino K Sumiyoshi S Yoshimura N
author_sort	Hata M
title	Conjunctival extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue in the fornix: do not overlook conjunctival lymphomas
title_short	Conjunctival extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue in the fornix: do not overlook conjunctival lymphomas
title_full	Conjunctival extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue in the fornix: do not overlook conjunctival lymphomas
title_fullStr	Conjunctival extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue in the fornix: do not overlook conjunctival lymphomas
title_full_unstemmed	Conjunctival extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue in the fornix: do not overlook conjunctival lymphomas
title_sort	conjunctival extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue in the fornix: do not overlook conjunctival lymphomas
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/e74b1ee2f3f44ac4833f552870a13a31
work_keys_str_mv	AT hatam conjunctivalextranodalmarginalzonelymphomaofmucosaassociatedlymphoidtissueinthefornixdonotoverlookconjunctivallymphomas AT miyamotok conjunctivalextranodalmarginalzonelymphomaofmucosaassociatedlymphoidtissueinthefornixdonotoverlookconjunctivallymphomas AT oginok conjunctivalextranodalmarginalzonelymphomaofmucosaassociatedlymphoidtissueinthefornixdonotoverlookconjunctivallymphomas AT sumiyoshis conjunctivalextranodalmarginalzonelymphomaofmucosaassociatedlymphoidtissueinthefornixdonotoverlookconjunctivallymphomas AT yoshimuran conjunctivalextranodalmarginalzonelymphomaofmucosaassociatedlymphoidtissueinthefornixdonotoverlookconjunctivallymphomas
_version_	1718400566767386624

Conjunctival extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue in the fornix: do not overlook conjunctival lymphomas

Ejemplares similares