Comparison of recovery duration of Propofol and Thiopental Sodium in ECT

Background and objective: Thiopental sodium is not and ideal intravenous drug for inducing general anesthesia and compared to intravenous anesthetic drugs like propofol has a long standing recovery time. The aim of this study was to compare the recovery duration of propofol and thiopental sodium in...

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Autores principales:	H Ale Reza, E Alijan Pour, M Rabiei, P Amri, SM Elmi, F Kheir Khah
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2005
Materias:	propofol thiopental sodium ect anesthetic induction recovery Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/e750a457cec04005821d7b09d759952e
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spelling	oai:doaj.org-article:e750a457cec04005821d7b09d759952e2021-11-10T09:14:41ZComparison of recovery duration of Propofol and Thiopental Sodium in ECT1561-41072251-7170https://doaj.org/article/e750a457cec04005821d7b09d759952e2005-07-01T00:00:00Zhttp://jbums.org/article-1-2621-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170Background and objective: Thiopental sodium is not and ideal intravenous drug for inducing general anesthesia and compared to intravenous anesthetic drugs like propofol has a long standing recovery time. The aim of this study was to compare the recovery duration of propofol and thiopental sodium in ECT (Electroconvulsive therapy). Methods: In a clinical trial, 70 patients aged between 15-40 years old in ASA class I & II were selected for ECT. They were randomly divided into two groups of 35 patients. After patient monitoring, 2-3 mg/kg thiopental sodium or 1-1.5 mg/kg propofol (Randomly in each patient) and then 0.5 mg/kg succinylcholine were administered. Patients were ventilated with mask and oxygen (100%). After ECT, seizure and recovery durations were recorded. During these procedures, blood pressure and heart rate were recorded before and after anesthetic induction and 1 and 5 min after ECT. Findings: Mean recovery duration of propofol and thiopental sodium were 5.49±2.57 min and 6.4±3.69 min, respectively (P=0.233). Also, seizure duration of propofol and thiopental sodium were 32.06±13.78 sec and 35.06±10.08 sec (P=0.302). Hemodynamic changes (Systolic blood pressure) in two groups were not significant except at 1 minute after seizure (P<0.05). Conclusion: According to the results, there was not a significant difference between two groups in seizure and recovery duration. But propofol can prevent increasing hemodynamic response to ECT better than thiopental sodium. In patients with hypertension or restriction of thiopental sodium, propofol can be a suitable replacement.H Ale RezaE Alijan PourM RabieiP AmriSM ElmiF Kheir KhahBabol University of Medical Sciencesarticlepropofolthiopental sodiumectanesthetic inductionrecoveryMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 7, Iss 3, Pp 50-54 (2005)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	propofol thiopental sodium ect anesthetic induction recovery Medicine R Medicine (General) R5-920
spellingShingle	propofol thiopental sodium ect anesthetic induction recovery Medicine R Medicine (General) R5-920 H Ale Reza E Alijan Pour M Rabiei P Amri SM Elmi F Kheir Khah Comparison of recovery duration of Propofol and Thiopental Sodium in ECT
description	Background and objective: Thiopental sodium is not and ideal intravenous drug for inducing general anesthesia and compared to intravenous anesthetic drugs like propofol has a long standing recovery time. The aim of this study was to compare the recovery duration of propofol and thiopental sodium in ECT (Electroconvulsive therapy). Methods: In a clinical trial, 70 patients aged between 15-40 years old in ASA class I & II were selected for ECT. They were randomly divided into two groups of 35 patients. After patient monitoring, 2-3 mg/kg thiopental sodium or 1-1.5 mg/kg propofol (Randomly in each patient) and then 0.5 mg/kg succinylcholine were administered. Patients were ventilated with mask and oxygen (100%). After ECT, seizure and recovery durations were recorded. During these procedures, blood pressure and heart rate were recorded before and after anesthetic induction and 1 and 5 min after ECT. Findings: Mean recovery duration of propofol and thiopental sodium were 5.49±2.57 min and 6.4±3.69 min, respectively (P=0.233). Also, seizure duration of propofol and thiopental sodium were 32.06±13.78 sec and 35.06±10.08 sec (P=0.302). Hemodynamic changes (Systolic blood pressure) in two groups were not significant except at 1 minute after seizure (P<0.05). Conclusion: According to the results, there was not a significant difference between two groups in seizure and recovery duration. But propofol can prevent increasing hemodynamic response to ECT better than thiopental sodium. In patients with hypertension or restriction of thiopental sodium, propofol can be a suitable replacement.
format	article
author	H Ale Reza E Alijan Pour M Rabiei P Amri SM Elmi F Kheir Khah
author_facet	H Ale Reza E Alijan Pour M Rabiei P Amri SM Elmi F Kheir Khah
author_sort	H Ale Reza
title	Comparison of recovery duration of Propofol and Thiopental Sodium in ECT
title_short	Comparison of recovery duration of Propofol and Thiopental Sodium in ECT
title_full	Comparison of recovery duration of Propofol and Thiopental Sodium in ECT
title_fullStr	Comparison of recovery duration of Propofol and Thiopental Sodium in ECT
title_full_unstemmed	Comparison of recovery duration of Propofol and Thiopental Sodium in ECT
title_sort	comparison of recovery duration of propofol and thiopental sodium in ect
publisher	Babol University of Medical Sciences
publishDate	2005
url	https://doaj.org/article/e750a457cec04005821d7b09d759952e
work_keys_str_mv	AT halereza comparisonofrecoverydurationofpropofolandthiopentalsodiuminect AT ealijanpour comparisonofrecoverydurationofpropofolandthiopentalsodiuminect AT mrabiei comparisonofrecoverydurationofpropofolandthiopentalsodiuminect AT pamri comparisonofrecoverydurationofpropofolandthiopentalsodiuminect AT smelmi comparisonofrecoverydurationofpropofolandthiopentalsodiuminect AT fkheirkhah comparisonofrecoverydurationofpropofolandthiopentalsodiuminect
_version_	1718440244536147968

Comparison of recovery duration of Propofol and Thiopental Sodium in ECT

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