PARP-1 overexpression contributes to Cadmium-induced death in rat proximal tubular cells via parthanatos and the MAPK signalling pathway

PARP-1 overexpression contributes to Cadmium-induced death in rat proximal tubular cells via parthanatos and the MAPK signalling pathway

Abstract Parthanatos is a newly discovered form of PARP-1-dependent programmed cell death. It has been reported to play an important role in several cancer or tumour cells; however, few studies have been performed in normal cells. Cadmium is a highly toxic pollutant and is reported to induce autopha...

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Autores principales: Tongwang Luo, Yan Yuan, Qi Yu, Gang Liu, Mengfei Long, Kanglei Zhang, Jianchun Bian, Jianhong Gu, Hui Zou, Yi Wang, Jiaqiao Zhu, Xuezhong Liu, Zongping Liu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/e757d754e9234495baf77a7f02ab3bc0
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