Automated high-throughput heartbeat quantification in medaka and zebrafish embryos under physiological conditions
Abstract Accurate quantification of heartbeats in fish models is an important readout to study cardiovascular biology, disease states and pharmacology. However, dependence on anaesthesia, laborious sample orientation or requirement for fluorescent reporters have hampered the use of high-throughput h...
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Autores principales: | Jakob Gierten, Christian Pylatiuk, Omar T. Hammouda, Christian Schock, Johannes Stegmaier, Joachim Wittbrodt, Jochen Gehrig, Felix Loosli |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/e7599b73afdf4766a3526d1359de26d9 |
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