One-year analysis of the iStent trabecular microbypass in secondary glaucoma

Oscar Buchacra, Susana Duch, Elena Milla, Oana StirbuDepartment of Ophthalmology, Instituto Condal de Oftalmolog&iacute;a, Barcelona, SpainPurpose: To evaluate the midterm efficacy and safety of the iStent&reg; glaucoma device in patients with secondary open-angle glaucoma.Patients a...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Oscar Buchacra, Susana Duch, Elena Milla, et al
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2011
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/e7638c790c684c2290789d009a01a68b
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:e7638c790c684c2290789d009a01a68b
record_format	dspace
spelling	oai:doaj.org-article:e7638c790c684c2290789d009a01a68b2021-12-02T05:40:56ZOne-year analysis of the iStent trabecular microbypass in secondary glaucoma1177-54671177-5483https://doaj.org/article/e7638c790c684c2290789d009a01a68b2011-03-01T00:00:00Zhttp://www.dovepress.com/one-year-analysis-of-the-istent-trabecular-microbypass-in-secondary-gl-a6567https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Oscar Buchacra, Susana Duch, Elena Milla, Oana StirbuDepartment of Ophthalmology, Instituto Condal de Oftalmolog&iacute;a, Barcelona, SpainPurpose: To evaluate the midterm efficacy and safety of the iStent&reg; glaucoma device in patients with secondary open-angle glaucoma.Patients and methods: A prospective, nonrandomized, interventional case series involving 10 patients with secondary open-angle glaucoma (traumatic, steroid, pseudoexfoliative, and pigmentary glaucoma) of recent onset who underwent ab interno implantation iStent. Patients were assessed following the procedure on days 1, 7, and 15 and months 1, 3, 6, and 12, and examinations included visual acuity, intraocular pressure (IOP) measurement using Goldmann tonometry, number of glaucoma medications, and complications. Wilcoxon rank-test for data with abnormal distribution was used for the analysis of IOP and glaucoma medications at baseline versus 3, 6, and 12 months following the procedure.Results: The mean baseline IOP was 26.5 &plusmn; 7.9 (range 18&ndash;40) mmHg, and significantly decreased in 10.4 &plusmn; 9.2 mmHg at three months (P &lt; 0.05), in 7.4 &plusmn; 4.9 mmHg at six months (P &lt; 0.05), and in 6.6 &plusmn; 5.4 mmHg at 12 months (P &lt; 0.05) following iStent implantation. The mean number of hypotensive medications at baseline was 2.9 &plusmn; 0.7 (range 2&ndash;4). Statistically significant reductions in the number of medications of 1.1 &plusmn; 1.1 were observed at three months (P &lt; 0.05), 1.0 &plusmn; 0.7 at six months (P &lt; 0.05), and 1.1 &plusmn; 0.6 at 12 months (P &lt; 0.05). No significant changes in visual acuity were noted. The most common complications comprised mild hyphema in seven eyes and transient IOP &ge; 30 mmHg in three eyes on postoperative day 1. Obstruction of the lumen of the stent with a blood clot was seen in three eyes, and all instances resolved spontaneously.Conclusion: The iStent is a safe and effective treatment option in patients with secondary open-angle glaucoma, and reduces the topical treatment burden in one hypotensive medication.Keywords: traumatic, steroid, pseudoexfoliative, pigmentary, stent Oscar BuchacraSusana DuchElena Millaet alDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2011, Iss default, Pp 321-326 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Oscar Buchacra Susana Duch Elena Milla et al One-year analysis of the iStent trabecular microbypass in secondary glaucoma
description	Oscar Buchacra, Susana Duch, Elena Milla, Oana StirbuDepartment of Ophthalmology, Instituto Condal de Oftalmolog&iacute;a, Barcelona, SpainPurpose: To evaluate the midterm efficacy and safety of the iStent&reg; glaucoma device in patients with secondary open-angle glaucoma.Patients and methods: A prospective, nonrandomized, interventional case series involving 10 patients with secondary open-angle glaucoma (traumatic, steroid, pseudoexfoliative, and pigmentary glaucoma) of recent onset who underwent ab interno implantation iStent. Patients were assessed following the procedure on days 1, 7, and 15 and months 1, 3, 6, and 12, and examinations included visual acuity, intraocular pressure (IOP) measurement using Goldmann tonometry, number of glaucoma medications, and complications. Wilcoxon rank-test for data with abnormal distribution was used for the analysis of IOP and glaucoma medications at baseline versus 3, 6, and 12 months following the procedure.Results: The mean baseline IOP was 26.5 &plusmn; 7.9 (range 18&ndash;40) mmHg, and significantly decreased in 10.4 &plusmn; 9.2 mmHg at three months (P &lt; 0.05), in 7.4 &plusmn; 4.9 mmHg at six months (P &lt; 0.05), and in 6.6 &plusmn; 5.4 mmHg at 12 months (P &lt; 0.05) following iStent implantation. The mean number of hypotensive medications at baseline was 2.9 &plusmn; 0.7 (range 2&ndash;4). Statistically significant reductions in the number of medications of 1.1 &plusmn; 1.1 were observed at three months (P &lt; 0.05), 1.0 &plusmn; 0.7 at six months (P &lt; 0.05), and 1.1 &plusmn; 0.6 at 12 months (P &lt; 0.05). No significant changes in visual acuity were noted. The most common complications comprised mild hyphema in seven eyes and transient IOP &ge; 30 mmHg in three eyes on postoperative day 1. Obstruction of the lumen of the stent with a blood clot was seen in three eyes, and all instances resolved spontaneously.Conclusion: The iStent is a safe and effective treatment option in patients with secondary open-angle glaucoma, and reduces the topical treatment burden in one hypotensive medication.Keywords: traumatic, steroid, pseudoexfoliative, pigmentary, stent
format	article
author	Oscar Buchacra Susana Duch Elena Milla et al
author_facet	Oscar Buchacra Susana Duch Elena Milla et al
author_sort	Oscar Buchacra
title	One-year analysis of the iStent trabecular microbypass in secondary glaucoma
title_short	One-year analysis of the iStent trabecular microbypass in secondary glaucoma
title_full	One-year analysis of the iStent trabecular microbypass in secondary glaucoma
title_fullStr	One-year analysis of the iStent trabecular microbypass in secondary glaucoma
title_full_unstemmed	One-year analysis of the iStent trabecular microbypass in secondary glaucoma
title_sort	one-year analysis of the istent trabecular microbypass in secondary glaucoma
publisher	Dove Medical Press
publishDate	2011
url	https://doaj.org/article/e7638c790c684c2290789d009a01a68b
work_keys_str_mv	AT oscarbuchacra oneyearanalysisoftheistenttrabecularmicrobypassinsecondaryglaucoma AT susanaduch oneyearanalysisoftheistenttrabecularmicrobypassinsecondaryglaucoma AT elenamilla oneyearanalysisoftheistenttrabecularmicrobypassinsecondaryglaucoma AT etal oneyearanalysisoftheistenttrabecularmicrobypassinsecondaryglaucoma
_version_	1718400327813693440

One-year analysis of the iStent trabecular microbypass in secondary glaucoma

Ejemplares similares