Centrosomal localization of the psoriasis candidate gene product, CCHCR1, supports a role in cytoskeletal organization.
CCHCR1 (Coiled-Coil α-Helical Rod protein 1), within the major psoriasis susceptibility locus PSORS1, is a plausible candidate gene with the psoriasis associated risk allele CCHCR1*WWCC. Although its expression pattern in psoriatic skin differs from healthy skin and its overexpression influences cel...
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Main Authors: | Mari H Tervaniemi, H Annika Siitonen, Cilla Söderhäll, Gurinder Minhas, Jyrki Vuola, Inkeri Tiala, Raija Sormunen, Lena Samuelsson, Sari Suomela, Juha Kere, Outi Elomaa |
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Format: | article |
Language: | EN |
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Public Library of Science (PLoS)
2012
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Online Access: | https://doaj.org/article/e766049596e5457c8f30b1ee4cca5b82 |
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