Extracellular matrix stiffness cues junctional remodeling for 3D tissue elongation

The extracellular matrix can shape developing organs, but how external forces direct intercellular morphogenesis is unclear. Here, the authors use 3D imaging to show that elongation of the Drosophila egg chamber involves polarized cell reorientation signalled by changes in stiffness of the surroundi...

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Autores principales:	Dong-Yuan Chen, Justin Crest, Sebastian J. Streichan, David Bilder
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e771acac7c584a05a3c17ffd57e94efa
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id	oai:doaj.org-article:e771acac7c584a05a3c17ffd57e94efa
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spelling	oai:doaj.org-article:e771acac7c584a05a3c17ffd57e94efa2021-12-02T15:36:21ZExtracellular matrix stiffness cues junctional remodeling for 3D tissue elongation10.1038/s41467-019-10874-x2041-1723https://doaj.org/article/e771acac7c584a05a3c17ffd57e94efa2019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10874-xhttps://doaj.org/toc/2041-1723The extracellular matrix can shape developing organs, but how external forces direct intercellular morphogenesis is unclear. Here, the authors use 3D imaging to show that elongation of the Drosophila egg chamber involves polarized cell reorientation signalled by changes in stiffness of the surrounding extracellular matrix.Dong-Yuan ChenJustin CrestSebastian J. StreichanDavid BilderNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Dong-Yuan Chen Justin Crest Sebastian J. Streichan David Bilder Extracellular matrix stiffness cues junctional remodeling for 3D tissue elongation
description	The extracellular matrix can shape developing organs, but how external forces direct intercellular morphogenesis is unclear. Here, the authors use 3D imaging to show that elongation of the Drosophila egg chamber involves polarized cell reorientation signalled by changes in stiffness of the surrounding extracellular matrix.
format	article
author	Dong-Yuan Chen Justin Crest Sebastian J. Streichan David Bilder
author_facet	Dong-Yuan Chen Justin Crest Sebastian J. Streichan David Bilder
author_sort	Dong-Yuan Chen
title	Extracellular matrix stiffness cues junctional remodeling for 3D tissue elongation
title_short	Extracellular matrix stiffness cues junctional remodeling for 3D tissue elongation
title_full	Extracellular matrix stiffness cues junctional remodeling for 3D tissue elongation
title_fullStr	Extracellular matrix stiffness cues junctional remodeling for 3D tissue elongation
title_full_unstemmed	Extracellular matrix stiffness cues junctional remodeling for 3D tissue elongation
title_sort	extracellular matrix stiffness cues junctional remodeling for 3d tissue elongation
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/e771acac7c584a05a3c17ffd57e94efa
work_keys_str_mv	AT dongyuanchen extracellularmatrixstiffnesscuesjunctionalremodelingfor3dtissueelongation AT justincrest extracellularmatrixstiffnesscuesjunctionalremodelingfor3dtissueelongation AT sebastianjstreichan extracellularmatrixstiffnesscuesjunctionalremodelingfor3dtissueelongation AT davidbilder extracellularmatrixstiffnesscuesjunctionalremodelingfor3dtissueelongation
_version_	1718386322557632512

Extracellular matrix stiffness cues junctional remodeling for 3D tissue elongation

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