Oral Bacteria and Colorectal Pathology
Context- The oral cavity and the colon, though part of the alimentary tract are distantly located anatomically and hence are colonized by totally divergent microbes. The mouth is affected by several pathologies and so is the colon. So it is quite natural to investigate the probable connection betwee...
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Shiraz University of Medical Sciences
2021
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oai:doaj.org-article:e775277f42d1416bb4f00c38ee02f12b2021-11-14T06:50:42ZOral Bacteria and Colorectal Pathology2783-243010.30476/acrr.2021.91493.1105https://doaj.org/article/e775277f42d1416bb4f00c38ee02f12b2021-06-01T00:00:00Zhttps://colorectalresearch.sums.ac.ir/article_47684_bf86bec632d357a4553600c63e6d62fc.pdfhttps://doaj.org/toc/2783-2430Context- The oral cavity and the colon, though part of the alimentary tract are distantly located anatomically and hence are colonized by totally divergent microbes. The mouth is affected by several pathologies and so is the colon. So it is quite natural to investigate the probable connection between poor oral health and colorectal pathologies. Evidence acquisition- This article is a small attempt to identify the oral microbiota, how they translocate to the colon-rectum area and then how do they create pathology there. Pubmed indexed journals relating to this topic were screened and shortlisted to construct this article. Results- The organisms generally responsible for the oral diseases, namely Fusobacterium nucleatum and Porphyromonas gingivalis among others have been found in colon disorders resulting in intestinal dysbiosis and ultimately leading to colorectal cancer. Conclusions- If the disease pathogenesis is well understood, then it will open new ways on how to prevent or treat colorectal pathologies. However further studies are needed in this arena.Vineet NairShiraz University of Medical Sciencesarticlecolorectal cancerdysbiosismicrobiotaperiodontitisMedicineRENIranian Journal of Colorectal Research, Vol 9, Iss 2, Pp 47-50 (2021) |
institution |
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DOAJ |
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EN |
topic |
colorectal cancer dysbiosis microbiota periodontitis Medicine R |
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colorectal cancer dysbiosis microbiota periodontitis Medicine R Vineet Nair Oral Bacteria and Colorectal Pathology |
description |
Context- The oral cavity and the colon, though part of the alimentary tract are distantly located anatomically and hence are colonized by totally divergent microbes. The mouth is affected by several pathologies and so is the colon. So it is quite natural to investigate the probable connection between poor oral health and colorectal pathologies. Evidence acquisition- This article is a small attempt to identify the oral microbiota, how they translocate to the colon-rectum area and then how do they create pathology there. Pubmed indexed journals relating to this topic were screened and shortlisted to construct this article. Results- The organisms generally responsible for the oral diseases, namely Fusobacterium nucleatum and Porphyromonas gingivalis among others have been found in colon disorders resulting in intestinal dysbiosis and ultimately leading to colorectal cancer. Conclusions- If the disease pathogenesis is well understood, then it will open new ways on how to prevent or treat colorectal pathologies. However further studies are needed in this arena. |
format |
article |
author |
Vineet Nair |
author_facet |
Vineet Nair |
author_sort |
Vineet Nair |
title |
Oral Bacteria and Colorectal Pathology |
title_short |
Oral Bacteria and Colorectal Pathology |
title_full |
Oral Bacteria and Colorectal Pathology |
title_fullStr |
Oral Bacteria and Colorectal Pathology |
title_full_unstemmed |
Oral Bacteria and Colorectal Pathology |
title_sort |
oral bacteria and colorectal pathology |
publisher |
Shiraz University of Medical Sciences |
publishDate |
2021 |
url |
https://doaj.org/article/e775277f42d1416bb4f00c38ee02f12b |
work_keys_str_mv |
AT vineetnair oralbacteriaandcolorectalpathology |
_version_ |
1718429871315615744 |