Oral Bacteria and Colorectal Pathology

Context- The oral cavity and the colon, though part of the alimentary tract are distantly located anatomically and hence are colonized by totally divergent microbes. The mouth is affected by several pathologies and so is the colon. So it is quite natural to investigate the probable connection betwee...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autor principal: Vineet Nair
Formato: article
Lenguaje:EN
Publicado: Shiraz University of Medical Sciences 2021
Materias:
R
Acceso en línea:https://doaj.org/article/e775277f42d1416bb4f00c38ee02f12b
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:e775277f42d1416bb4f00c38ee02f12b
record_format dspace
spelling oai:doaj.org-article:e775277f42d1416bb4f00c38ee02f12b2021-11-14T06:50:42ZOral Bacteria and Colorectal Pathology2783-243010.30476/acrr.2021.91493.1105https://doaj.org/article/e775277f42d1416bb4f00c38ee02f12b2021-06-01T00:00:00Zhttps://colorectalresearch.sums.ac.ir/article_47684_bf86bec632d357a4553600c63e6d62fc.pdfhttps://doaj.org/toc/2783-2430Context- The oral cavity and the colon, though part of the alimentary tract are distantly located anatomically and hence are colonized by totally divergent microbes. The mouth is affected by several pathologies and so is the colon. So it is quite natural to investigate the probable connection between poor oral health and colorectal pathologies. Evidence acquisition- This article is a small attempt to identify the oral microbiota, how they translocate to the colon-rectum area and then how do they create pathology there. Pubmed indexed journals relating to this topic were screened and shortlisted to construct this article. Results- The organisms generally responsible for the oral diseases, namely Fusobacterium nucleatum and Porphyromonas gingivalis among others have been found in colon disorders resulting in intestinal dysbiosis and ultimately leading to colorectal cancer. Conclusions- If the disease pathogenesis is well understood, then it will open new ways on how to prevent or treat colorectal pathologies. However further studies are needed in this arena.Vineet NairShiraz University of Medical Sciencesarticlecolorectal cancerdysbiosismicrobiotaperiodontitisMedicineRENIranian Journal of Colorectal Research, Vol 9, Iss 2, Pp 47-50 (2021)
institution DOAJ
collection DOAJ
language EN
topic colorectal cancer
dysbiosis
microbiota
periodontitis
Medicine
R
spellingShingle colorectal cancer
dysbiosis
microbiota
periodontitis
Medicine
R
Vineet Nair
Oral Bacteria and Colorectal Pathology
description Context- The oral cavity and the colon, though part of the alimentary tract are distantly located anatomically and hence are colonized by totally divergent microbes. The mouth is affected by several pathologies and so is the colon. So it is quite natural to investigate the probable connection between poor oral health and colorectal pathologies. Evidence acquisition- This article is a small attempt to identify the oral microbiota, how they translocate to the colon-rectum area and then how do they create pathology there. Pubmed indexed journals relating to this topic were screened and shortlisted to construct this article. Results- The organisms generally responsible for the oral diseases, namely Fusobacterium nucleatum and Porphyromonas gingivalis among others have been found in colon disorders resulting in intestinal dysbiosis and ultimately leading to colorectal cancer. Conclusions- If the disease pathogenesis is well understood, then it will open new ways on how to prevent or treat colorectal pathologies. However further studies are needed in this arena.
format article
author Vineet Nair
author_facet Vineet Nair
author_sort Vineet Nair
title Oral Bacteria and Colorectal Pathology
title_short Oral Bacteria and Colorectal Pathology
title_full Oral Bacteria and Colorectal Pathology
title_fullStr Oral Bacteria and Colorectal Pathology
title_full_unstemmed Oral Bacteria and Colorectal Pathology
title_sort oral bacteria and colorectal pathology
publisher Shiraz University of Medical Sciences
publishDate 2021
url https://doaj.org/article/e775277f42d1416bb4f00c38ee02f12b
work_keys_str_mv AT vineetnair oralbacteriaandcolorectalpathology
_version_ 1718429871315615744