Recombinant herpesvirus glycoprotein G improves the protective immune response to Helicobacter pylori vaccination in a mouse model of disease.
Alphaherpesviruses, which have co-evolved with their hosts for more than 200 million years, evade and subvert host immune responses, in part, by expression of immuno-modulatory molecules. Alphaherpesviruses express a single, broadly conserved chemokine decoy receptor, glycoprotein G (gG), which can...
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Main Authors: | Louise Baker, Andre M L Chitas, Carol A Hartley, Mauricio J C Coppo, Paola K Vaz, Andrew Stent, James R Gilkerson, Joanne M Devlin, Alison L Every |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2014
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Online Access: | https://doaj.org/article/e77ce459c55a4e2189fdf39e8217553b |
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