Chirality imprinting and direct asymmetric reaction screening using a stereodynamic Brønsted/Lewis acid receptor
Determining results of asymmetric reactions can take long periods of time and consume large amounts of organic solvents during work-up and analysis. Here, the authors report a bifunctional organic probe that can bind to chiral hydroxyacids, and provide yield, enantiomeric excess and absolute configu...
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Autores principales: | , , |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
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Materias: | |
Acceso en línea: | https://doaj.org/article/e77f8baa04984dda8c81a509c2b86eab |
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Sumario: | Determining results of asymmetric reactions can take long periods of time and consume large amounts of organic solvents during work-up and analysis. Here, the authors report a bifunctional organic probe that can bind to chiral hydroxyacids, and provide yield, enantiomeric excess and absolute configuration even with crude mixtures. |
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