Chirality imprinting and direct asymmetric reaction screening using a stereodynamic Brønsted/Lewis acid receptor
Determining results of asymmetric reactions can take long periods of time and consume large amounts of organic solvents during work-up and analysis. Here, the authors report a bifunctional organic probe that can bind to chiral hydroxyacids, and provide yield, enantiomeric excess and absolute configu...
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Nature Portfolio
2016
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oai:doaj.org-article:e77f8baa04984dda8c81a509c2b86eab2021-12-02T16:57:29ZChirality imprinting and direct asymmetric reaction screening using a stereodynamic Brønsted/Lewis acid receptor10.1038/ncomms125392041-1723https://doaj.org/article/e77f8baa04984dda8c81a509c2b86eab2016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12539https://doaj.org/toc/2041-1723Determining results of asymmetric reactions can take long periods of time and consume large amounts of organic solvents during work-up and analysis. Here, the authors report a bifunctional organic probe that can bind to chiral hydroxyacids, and provide yield, enantiomeric excess and absolute configuration even with crude mixtures.Keith W. BentleyDaysi ProanoChristian WolfNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016) |
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Science Q Keith W. Bentley Daysi Proano Christian Wolf Chirality imprinting and direct asymmetric reaction screening using a stereodynamic Brønsted/Lewis acid receptor |
description |
Determining results of asymmetric reactions can take long periods of time and consume large amounts of organic solvents during work-up and analysis. Here, the authors report a bifunctional organic probe that can bind to chiral hydroxyacids, and provide yield, enantiomeric excess and absolute configuration even with crude mixtures. |
format |
article |
author |
Keith W. Bentley Daysi Proano Christian Wolf |
author_facet |
Keith W. Bentley Daysi Proano Christian Wolf |
author_sort |
Keith W. Bentley |
title |
Chirality imprinting and direct asymmetric reaction screening using a stereodynamic Brønsted/Lewis acid receptor |
title_short |
Chirality imprinting and direct asymmetric reaction screening using a stereodynamic Brønsted/Lewis acid receptor |
title_full |
Chirality imprinting and direct asymmetric reaction screening using a stereodynamic Brønsted/Lewis acid receptor |
title_fullStr |
Chirality imprinting and direct asymmetric reaction screening using a stereodynamic Brønsted/Lewis acid receptor |
title_full_unstemmed |
Chirality imprinting and direct asymmetric reaction screening using a stereodynamic Brønsted/Lewis acid receptor |
title_sort |
chirality imprinting and direct asymmetric reaction screening using a stereodynamic brønsted/lewis acid receptor |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/e77f8baa04984dda8c81a509c2b86eab |
work_keys_str_mv |
AT keithwbentley chiralityimprintinganddirectasymmetricreactionscreeningusingastereodynamicbrønstedlewisacidreceptor AT daysiproano chiralityimprintinganddirectasymmetricreactionscreeningusingastereodynamicbrønstedlewisacidreceptor AT christianwolf chiralityimprintinganddirectasymmetricreactionscreeningusingastereodynamicbrønstedlewisacidreceptor |
_version_ |
1718382596436525056 |