Three-dimensional low shear culture of Mycobacterium bovis BCG induces biofilm formation and antimicrobial drug tolerance

Abstract Mycobacteria naturally grow as corded biofilms in liquid media without detergent. Such detergent-free biofilm phenotypes may reflect the growth pattern of bacilli in tuberculous lung lesions. New strategies are required to treat tuberculosis, which is responsible for more deaths each year t...

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Bibliographic Details
Main Authors: Daire Cantillon, Justyna Wroblewska, Ian Cooper, Melanie J. Newport, Simon J. Waddell
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/e7819f1bcebf4e7a86cd42bb30477b29
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