Evolutionary conservation and in vitro reconstitution of microsporidian iron–sulfur cluster biosynthesis

The functions of the highly reduced mitochondria (mitosomes) of microsporidians are not well-characterized. Here, the authors show that theTrachipleistophora hominismitosome is the site of iron–sulfur cluster assembly and that its retention is likely linked to its role in cytosolic and nuclear iron–...

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Autores principales:	Sven-A. Freibert, Alina V. Goldberg, Christian Hacker, Sabine Molik, Paul Dean, Tom A. Williams, Sirintra Nakjang, Shaojun Long, Kacper Sendra, Eckhard Bill, Eva Heinz, Robert P. Hirt, John M Lucocq, T. Martin Embley, Roland Lill
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e78ff76691884b4cabe49d811630fe3d
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spelling	oai:doaj.org-article:e78ff76691884b4cabe49d811630fe3d2021-12-02T17:06:01ZEvolutionary conservation and in vitro reconstitution of microsporidian iron–sulfur cluster biosynthesis10.1038/ncomms139322041-1723https://doaj.org/article/e78ff76691884b4cabe49d811630fe3d2017-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms13932https://doaj.org/toc/2041-1723The functions of the highly reduced mitochondria (mitosomes) of microsporidians are not well-characterized. Here, the authors show that theTrachipleistophora hominismitosome is the site of iron–sulfur cluster assembly and that its retention is likely linked to its role in cytosolic and nuclear iron–sulfur protein maturation.Sven-A. FreibertAlina V. GoldbergChristian HackerSabine MolikPaul DeanTom A. WilliamsSirintra NakjangShaojun LongKacper SendraEckhard BillEva HeinzRobert P. HirtJohn M LucocqT. Martin EmbleyRoland LillNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sven-A. Freibert Alina V. Goldberg Christian Hacker Sabine Molik Paul Dean Tom A. Williams Sirintra Nakjang Shaojun Long Kacper Sendra Eckhard Bill Eva Heinz Robert P. Hirt John M Lucocq T. Martin Embley Roland Lill Evolutionary conservation and in vitro reconstitution of microsporidian iron–sulfur cluster biosynthesis
description	The functions of the highly reduced mitochondria (mitosomes) of microsporidians are not well-characterized. Here, the authors show that theTrachipleistophora hominismitosome is the site of iron–sulfur cluster assembly and that its retention is likely linked to its role in cytosolic and nuclear iron–sulfur protein maturation.
format	article
author	Sven-A. Freibert Alina V. Goldberg Christian Hacker Sabine Molik Paul Dean Tom A. Williams Sirintra Nakjang Shaojun Long Kacper Sendra Eckhard Bill Eva Heinz Robert P. Hirt John M Lucocq T. Martin Embley Roland Lill
author_facet	Sven-A. Freibert Alina V. Goldberg Christian Hacker Sabine Molik Paul Dean Tom A. Williams Sirintra Nakjang Shaojun Long Kacper Sendra Eckhard Bill Eva Heinz Robert P. Hirt John M Lucocq T. Martin Embley Roland Lill
author_sort	Sven-A. Freibert
title	Evolutionary conservation and in vitro reconstitution of microsporidian iron–sulfur cluster biosynthesis
title_short	Evolutionary conservation and in vitro reconstitution of microsporidian iron–sulfur cluster biosynthesis
title_full	Evolutionary conservation and in vitro reconstitution of microsporidian iron–sulfur cluster biosynthesis
title_fullStr	Evolutionary conservation and in vitro reconstitution of microsporidian iron–sulfur cluster biosynthesis
title_full_unstemmed	Evolutionary conservation and in vitro reconstitution of microsporidian iron–sulfur cluster biosynthesis
title_sort	evolutionary conservation and in vitro reconstitution of microsporidian iron–sulfur cluster biosynthesis
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/e78ff76691884b4cabe49d811630fe3d
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Evolutionary conservation and in vitro reconstitution of microsporidian iron–sulfur cluster biosynthesis

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