The major secreted protein of the whipworm parasite tethers to matrix and inhibits interleukin-13 function

The major secreted protein of the whipworm parasite tethers to matrix and inhibits interleukin-13 function

In the study, the authors identify a protein excreted by the parasite Trichuris muris, p43, which can modulate IL-13 function, a key cytokine involved in host protection. These data suggest that p43 may be a novel therapeutic target for both whipworm infections and IL13 mediated pathologies.

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Allison J. Bancroft, Colin W. Levy, Thomas A. Jowitt, Kelly S. Hayes, Seona Thompson, Edward A. Mckenzie, Matthew D. Ball, Eamon Dubaissi, Aidan P. France, Bruno Bellina, Catherine Sharpe, Aleksandr Mironov, Sheila L. Brown, Peter C. Cook, Andrew S. MacDonald, David J. Thornton, Richard K. Grencis
Format: article
Langue:EN
Publié: Nature Portfolio 2019
Sujets:
Science
Q
Accès en ligne:https://doaj.org/article/e790a9921fd644c2949b6cd1e5687605
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Internet

https://doaj.org/article/e790a9921fd644c2949b6cd1e5687605

Documents similaires