Cytokines regulate the antigen-presenting characteristics of human circulating and tissue-resident intestinal ILCs
Murine ILCs can modulate T cell responses in MHCII-dependent manner. Here the authors show that human ILCs process and present antigens and induce T-cell responses upon exposure to IL-1-family cytokines; along with the article by Lehmann et al, this work elucidates how cytokines set context specific...
Guardado en:
Autores principales: | Anna Rao, Otto Strauss, Efthymia Kokkinou, Mélanie Bruchard, Kumar P. Tripathi, Heinrich Schlums, Anna Carrasco, Luca Mazzurana, Viktoria Konya, Eduardo J. Villablanca, Niklas K. Björkström, Ulrik Lindforss, Hergen Spits, Jenny Mjösberg |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/e79201d95ac34780b172a9be7f149a45 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
IL-1β, IL-23, and TGF-β drive plasticity of human ILC2s towards IL-17-producing ILCs in nasal inflammation
por: Korneliusz Golebski, et al.
Publicado: (2019) -
DR3 stimulation of adipose resident ILC2s ameliorates type 2 diabetes mellitus
por: Pedram Shafiei-Jahani, et al.
Publicado: (2020) -
IL-15 sustains IL-7R-independent ILC2 and ILC3 development
por: Michelle L. Robinette, et al.
Publicado: (2017) -
TGF-β induces ST2 and programs ILC2 development
por: Li Wang, et al.
Publicado: (2020) -
The Tec kinase ITK is essential for ILC2 survival and epithelial integrity in the intestine
por: Hyoung-Soo Cho, et al.
Publicado: (2019)