Global translation during early development depends on the essential transcription factor PRDM10

Global translation during early development depends on the essential transcription factor PRDM10

PRDM family members are transcriptional regulators involved in cell identity and fate determination. Here, the authors characterize PRDM10 and show that it functions to ensure global translation efficiency during early embryonic development.

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Bibliographic Details
Main Authors: Brenda Y. Han, Michelle K. Y. Seah, Imogen R. Brooks, Delia H. P. Quek, Dominic R. Huxley, Chuan-Sheng Foo, Li Ting Lee, Heike Wollmann, Huili Guo, Daniel M. Messerschmidt, Ernesto Guccione
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
Science
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Online Access:https://doaj.org/article/e7989e77dc6240d282d3dcdcea55b0b3
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Summary:PRDM family members are transcriptional regulators involved in cell identity and fate determination. Here, the authors characterize PRDM10 and show that it functions to ensure global translation efficiency during early embryonic development.

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