Global translation during early development depends on the essential transcription factor PRDM10
PRDM family members are transcriptional regulators involved in cell identity and fate determination. Here, the authors characterize PRDM10 and show that it functions to ensure global translation efficiency during early embryonic development.
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Nature Portfolio
2020
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oai:doaj.org-article:e7989e77dc6240d282d3dcdcea55b0b32021-12-02T17:01:15ZGlobal translation during early development depends on the essential transcription factor PRDM1010.1038/s41467-020-17304-32041-1723https://doaj.org/article/e7989e77dc6240d282d3dcdcea55b0b32020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17304-3https://doaj.org/toc/2041-1723PRDM family members are transcriptional regulators involved in cell identity and fate determination. Here, the authors characterize PRDM10 and show that it functions to ensure global translation efficiency during early embryonic development.Brenda Y. HanMichelle K. Y. SeahImogen R. BrooksDelia H. P. QuekDominic R. HuxleyChuan-Sheng FooLi Ting LeeHeike WollmannHuili GuoDaniel M. MesserschmidtErnesto GuccioneNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020) |
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Science Q Brenda Y. Han Michelle K. Y. Seah Imogen R. Brooks Delia H. P. Quek Dominic R. Huxley Chuan-Sheng Foo Li Ting Lee Heike Wollmann Huili Guo Daniel M. Messerschmidt Ernesto Guccione Global translation during early development depends on the essential transcription factor PRDM10 |
description |
PRDM family members are transcriptional regulators involved in cell identity and fate determination. Here, the authors characterize PRDM10 and show that it functions to ensure global translation efficiency during early embryonic development. |
format |
article |
author |
Brenda Y. Han Michelle K. Y. Seah Imogen R. Brooks Delia H. P. Quek Dominic R. Huxley Chuan-Sheng Foo Li Ting Lee Heike Wollmann Huili Guo Daniel M. Messerschmidt Ernesto Guccione |
author_facet |
Brenda Y. Han Michelle K. Y. Seah Imogen R. Brooks Delia H. P. Quek Dominic R. Huxley Chuan-Sheng Foo Li Ting Lee Heike Wollmann Huili Guo Daniel M. Messerschmidt Ernesto Guccione |
author_sort |
Brenda Y. Han |
title |
Global translation during early development depends on the essential transcription factor PRDM10 |
title_short |
Global translation during early development depends on the essential transcription factor PRDM10 |
title_full |
Global translation during early development depends on the essential transcription factor PRDM10 |
title_fullStr |
Global translation during early development depends on the essential transcription factor PRDM10 |
title_full_unstemmed |
Global translation during early development depends on the essential transcription factor PRDM10 |
title_sort |
global translation during early development depends on the essential transcription factor prdm10 |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/e7989e77dc6240d282d3dcdcea55b0b3 |
work_keys_str_mv |
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1718382245341822976 |