Global translation during early development depends on the essential transcription factor PRDM10

PRDM family members are transcriptional regulators involved in cell identity and fate determination. Here, the authors characterize PRDM10 and show that it functions to ensure global translation efficiency during early embryonic development.

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Autores principales: Brenda Y. Han, Michelle K. Y. Seah, Imogen R. Brooks, Delia H. P. Quek, Dominic R. Huxley, Chuan-Sheng Foo, Li Ting Lee, Heike Wollmann, Huili Guo, Daniel M. Messerschmidt, Ernesto Guccione
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/e7989e77dc6240d282d3dcdcea55b0b3
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spelling oai:doaj.org-article:e7989e77dc6240d282d3dcdcea55b0b32021-12-02T17:01:15ZGlobal translation during early development depends on the essential transcription factor PRDM1010.1038/s41467-020-17304-32041-1723https://doaj.org/article/e7989e77dc6240d282d3dcdcea55b0b32020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17304-3https://doaj.org/toc/2041-1723PRDM family members are transcriptional regulators involved in cell identity and fate determination. Here, the authors characterize PRDM10 and show that it functions to ensure global translation efficiency during early embryonic development.Brenda Y. HanMichelle K. Y. SeahImogen R. BrooksDelia H. P. QuekDominic R. HuxleyChuan-Sheng FooLi Ting LeeHeike WollmannHuili GuoDaniel M. MesserschmidtErnesto GuccioneNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Brenda Y. Han
Michelle K. Y. Seah
Imogen R. Brooks
Delia H. P. Quek
Dominic R. Huxley
Chuan-Sheng Foo
Li Ting Lee
Heike Wollmann
Huili Guo
Daniel M. Messerschmidt
Ernesto Guccione
Global translation during early development depends on the essential transcription factor PRDM10
description PRDM family members are transcriptional regulators involved in cell identity and fate determination. Here, the authors characterize PRDM10 and show that it functions to ensure global translation efficiency during early embryonic development.
format article
author Brenda Y. Han
Michelle K. Y. Seah
Imogen R. Brooks
Delia H. P. Quek
Dominic R. Huxley
Chuan-Sheng Foo
Li Ting Lee
Heike Wollmann
Huili Guo
Daniel M. Messerschmidt
Ernesto Guccione
author_facet Brenda Y. Han
Michelle K. Y. Seah
Imogen R. Brooks
Delia H. P. Quek
Dominic R. Huxley
Chuan-Sheng Foo
Li Ting Lee
Heike Wollmann
Huili Guo
Daniel M. Messerschmidt
Ernesto Guccione
author_sort Brenda Y. Han
title Global translation during early development depends on the essential transcription factor PRDM10
title_short Global translation during early development depends on the essential transcription factor PRDM10
title_full Global translation during early development depends on the essential transcription factor PRDM10
title_fullStr Global translation during early development depends on the essential transcription factor PRDM10
title_full_unstemmed Global translation during early development depends on the essential transcription factor PRDM10
title_sort global translation during early development depends on the essential transcription factor prdm10
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/e7989e77dc6240d282d3dcdcea55b0b3
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AT deliahpquek globaltranslationduringearlydevelopmentdependsontheessentialtranscriptionfactorprdm10
AT dominicrhuxley globaltranslationduringearlydevelopmentdependsontheessentialtranscriptionfactorprdm10
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