Focused ultrasound mediated blood–brain barrier opening is safe and feasible in a murine pontine glioma model
Abstract Drug delivery in diffuse intrinsic pontine glioma is significantly limited by the blood-brain barrier (BBB). Focused ultrasound (FUS), when combined with the administration of microbubbles can effectively open the BBB permitting the entry of drugs across the cerebrovasculature into the brai...
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Autores principales: | Zachary K. Englander, Hong-Jian Wei, Antonios N. Pouliopoulos, Ethan Bendau, Pavan Upadhyayula, Chia-Ing Jan, Eleanora F. Spinazzi, Nina Yoh, Masih Tazhibi, Nicholas M. McQuillan, Tony J. C. Wang, Jeffrey N. Bruce, Peter Canoll, Neil A. Feldstein, Stergios Zacharoulis, Elisa E. Konofagou, Cheng-Chia Wu |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/e7a089d62acc48338378a525c21513c4 |
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