Clinical appraisal of tafluprost in the reduction of elevated intraocular pressure (IOP) in open-angle glaucoma and ocular hypertension

Makoto AiharaDepartment of Ophthalmology, University of Tokyo School of Medicine, Tokyo, JapanAbstract: An elevated intraocular pressure (IOP) is one of the most important risk factors for the development of glaucoma, which causes progressive optic neuropathy. Lowering IOP is currently the only ther...

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Autor principal:	Makoto Aihara
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2010
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/e7b4aeeffb7a4d58be435fa98e06a802
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spelling	oai:doaj.org-article:e7b4aeeffb7a4d58be435fa98e06a8022021-12-02T07:09:40ZClinical appraisal of tafluprost in the reduction of elevated intraocular pressure (IOP) in open-angle glaucoma and ocular hypertension1177-54671177-5483https://doaj.org/article/e7b4aeeffb7a4d58be435fa98e06a8022010-03-01T00:00:00Zhttp://www.dovepress.com/clinical-appraisal-of-tafluprost-in-the-reduction-of-elevated-intraocu-a4105https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Makoto AiharaDepartment of Ophthalmology, University of Tokyo School of Medicine, Tokyo, JapanAbstract: An elevated intraocular pressure (IOP) is one of the most important risk factors for the development of glaucoma, which causes progressive optic neuropathy. Lowering IOP is currently the only therapeutic approach to the treatment of glaucoma. Tafluprost, a novel prostaglandin analogue, was recently launched onto the market as an ocular hypotensive agent. Tafluprost is potent in its affinity for the prostanoid FP receptor and in its intraocular lowering efficacy. Moreover, it enhances the ocular hemodynamics and has neuroprotective effects. Clinical studies have demonstrated its efficacy at decreasing intraocular pressure in patients with open-angle glaucoma or ocular hypertension.Keywords: open-angle glaucoma, normal tension glaucoma, receptor affinity, intraocular pressure Makoto AiharaDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2010, Iss default, Pp 163-170 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Makoto Aihara Clinical appraisal of tafluprost in the reduction of elevated intraocular pressure (IOP) in open-angle glaucoma and ocular hypertension
description	Makoto AiharaDepartment of Ophthalmology, University of Tokyo School of Medicine, Tokyo, JapanAbstract: An elevated intraocular pressure (IOP) is one of the most important risk factors for the development of glaucoma, which causes progressive optic neuropathy. Lowering IOP is currently the only therapeutic approach to the treatment of glaucoma. Tafluprost, a novel prostaglandin analogue, was recently launched onto the market as an ocular hypotensive agent. Tafluprost is potent in its affinity for the prostanoid FP receptor and in its intraocular lowering efficacy. Moreover, it enhances the ocular hemodynamics and has neuroprotective effects. Clinical studies have demonstrated its efficacy at decreasing intraocular pressure in patients with open-angle glaucoma or ocular hypertension.Keywords: open-angle glaucoma, normal tension glaucoma, receptor affinity, intraocular pressure
format	article
author	Makoto Aihara
author_facet	Makoto Aihara
author_sort	Makoto Aihara
title	Clinical appraisal of tafluprost in the reduction of elevated intraocular pressure (IOP) in open-angle glaucoma and ocular hypertension
title_short	Clinical appraisal of tafluprost in the reduction of elevated intraocular pressure (IOP) in open-angle glaucoma and ocular hypertension
title_full	Clinical appraisal of tafluprost in the reduction of elevated intraocular pressure (IOP) in open-angle glaucoma and ocular hypertension
title_fullStr	Clinical appraisal of tafluprost in the reduction of elevated intraocular pressure (IOP) in open-angle glaucoma and ocular hypertension
title_full_unstemmed	Clinical appraisal of tafluprost in the reduction of elevated intraocular pressure (IOP) in open-angle glaucoma and ocular hypertension
title_sort	clinical appraisal of tafluprost in the reduction of elevated intraocular pressure (iop) in open-angle glaucoma and ocular hypertension
publisher	Dove Medical Press
publishDate	2010
url	https://doaj.org/article/e7b4aeeffb7a4d58be435fa98e06a802
work_keys_str_mv	AT makotoaihara clinicalappraisaloftafluprostinthereductionofelevatedintraocularpressureiopinopenangleglaucomaandocularhypertension
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Clinical appraisal of tafluprost in the reduction of elevated intraocular pressure (IOP) in open-angle glaucoma and ocular hypertension

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