Evaluating the utility of syndromic case management for three sexually transmitted infections in women visiting hospitals in Delhi, India

Abstract Utility of syndromic case management (SCM) in women visiting obstetrics & gynecology department needs to be evaluated as it is subjective and imperfect. Consequently, antibiotic resistance has accelerated along with increased risk of infection to the partners. To understand the effectiv...

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Autores principales: Subash Chandra Sonkar, Kirti Wasnik, Anita Kumar, Vineeta Sharma, Pratima Mittal, Prashant Kumar Mishra, Mausumi Bharadwaj, Daman Saluja
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Publicado: Nature Portfolio 2017
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spelling oai:doaj.org-article:e7b774ef42894d9bb6db71b4530022132021-12-02T11:52:36ZEvaluating the utility of syndromic case management for three sexually transmitted infections in women visiting hospitals in Delhi, India10.1038/s41598-017-01422-y2045-2322https://doaj.org/article/e7b774ef42894d9bb6db71b4530022132017-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-01422-yhttps://doaj.org/toc/2045-2322Abstract Utility of syndromic case management (SCM) in women visiting obstetrics & gynecology department needs to be evaluated as it is subjective and imperfect. Consequently, antibiotic resistance has accelerated along with increased risk of infection to the partners. To understand the effectiveness and/or inadequacies of SCM, 11000 women were recruited and examined by clinicians for infection by Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), Trichomonas vaginalis (TV), Bacterial vaginosis (BV) and others. Amongst these patients, 1797 (16.3%) reported vaginal discharge (VD). Other symptoms included: vaginitis (97%), cervicitis (75%), genital ulcers (60%), abnormal vaginal discharge (55%) and lower abdominal pain (48%). The patients were treated for single or co-infections using pre-packed National Aids Control Program III STI/RTI Kits. However, based on PCR diagnostics, 1453/1797 (81%) subjects were uninfected for NG/TV/CT. Amongst 344 (19%) infected patients, 257 (75%) carried infection with single pathogen (TV/NG/CT) while 87/344 (25%) were co-infected with multiple pathogens. Prevalence of TV, NG & CT was 4%, 7% and 8% respectively. Co-infection with CT + NG was highest, 51% (44/87), whereas, co-infection with CT + TV was 21% and NG + TV was 18% while co-infection with all three pathogens was 1.3%. We conclude that SCM is imprecise and successful intervention requires accurate and confirmatory diagnostic approach.Subash Chandra SonkarKirti WasnikAnita KumarVineeta SharmaPratima MittalPrashant Kumar MishraMausumi BharadwajDaman SalujaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Subash Chandra Sonkar
Kirti Wasnik
Anita Kumar
Vineeta Sharma
Pratima Mittal
Prashant Kumar Mishra
Mausumi Bharadwaj
Daman Saluja
Evaluating the utility of syndromic case management for three sexually transmitted infections in women visiting hospitals in Delhi, India
description Abstract Utility of syndromic case management (SCM) in women visiting obstetrics & gynecology department needs to be evaluated as it is subjective and imperfect. Consequently, antibiotic resistance has accelerated along with increased risk of infection to the partners. To understand the effectiveness and/or inadequacies of SCM, 11000 women were recruited and examined by clinicians for infection by Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), Trichomonas vaginalis (TV), Bacterial vaginosis (BV) and others. Amongst these patients, 1797 (16.3%) reported vaginal discharge (VD). Other symptoms included: vaginitis (97%), cervicitis (75%), genital ulcers (60%), abnormal vaginal discharge (55%) and lower abdominal pain (48%). The patients were treated for single or co-infections using pre-packed National Aids Control Program III STI/RTI Kits. However, based on PCR diagnostics, 1453/1797 (81%) subjects were uninfected for NG/TV/CT. Amongst 344 (19%) infected patients, 257 (75%) carried infection with single pathogen (TV/NG/CT) while 87/344 (25%) were co-infected with multiple pathogens. Prevalence of TV, NG & CT was 4%, 7% and 8% respectively. Co-infection with CT + NG was highest, 51% (44/87), whereas, co-infection with CT + TV was 21% and NG + TV was 18% while co-infection with all three pathogens was 1.3%. We conclude that SCM is imprecise and successful intervention requires accurate and confirmatory diagnostic approach.
format article
author Subash Chandra Sonkar
Kirti Wasnik
Anita Kumar
Vineeta Sharma
Pratima Mittal
Prashant Kumar Mishra
Mausumi Bharadwaj
Daman Saluja
author_facet Subash Chandra Sonkar
Kirti Wasnik
Anita Kumar
Vineeta Sharma
Pratima Mittal
Prashant Kumar Mishra
Mausumi Bharadwaj
Daman Saluja
author_sort Subash Chandra Sonkar
title Evaluating the utility of syndromic case management for three sexually transmitted infections in women visiting hospitals in Delhi, India
title_short Evaluating the utility of syndromic case management for three sexually transmitted infections in women visiting hospitals in Delhi, India
title_full Evaluating the utility of syndromic case management for three sexually transmitted infections in women visiting hospitals in Delhi, India
title_fullStr Evaluating the utility of syndromic case management for three sexually transmitted infections in women visiting hospitals in Delhi, India
title_full_unstemmed Evaluating the utility of syndromic case management for three sexually transmitted infections in women visiting hospitals in Delhi, India
title_sort evaluating the utility of syndromic case management for three sexually transmitted infections in women visiting hospitals in delhi, india
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/e7b774ef42894d9bb6db71b453002213
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