Evaluating the utility of syndromic case management for three sexually transmitted infections in women visiting hospitals in Delhi, India
Abstract Utility of syndromic case management (SCM) in women visiting obstetrics & gynecology department needs to be evaluated as it is subjective and imperfect. Consequently, antibiotic resistance has accelerated along with increased risk of infection to the partners. To understand the effectiv...
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oai:doaj.org-article:e7b774ef42894d9bb6db71b4530022132021-12-02T11:52:36ZEvaluating the utility of syndromic case management for three sexually transmitted infections in women visiting hospitals in Delhi, India10.1038/s41598-017-01422-y2045-2322https://doaj.org/article/e7b774ef42894d9bb6db71b4530022132017-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-01422-yhttps://doaj.org/toc/2045-2322Abstract Utility of syndromic case management (SCM) in women visiting obstetrics & gynecology department needs to be evaluated as it is subjective and imperfect. Consequently, antibiotic resistance has accelerated along with increased risk of infection to the partners. To understand the effectiveness and/or inadequacies of SCM, 11000 women were recruited and examined by clinicians for infection by Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), Trichomonas vaginalis (TV), Bacterial vaginosis (BV) and others. Amongst these patients, 1797 (16.3%) reported vaginal discharge (VD). Other symptoms included: vaginitis (97%), cervicitis (75%), genital ulcers (60%), abnormal vaginal discharge (55%) and lower abdominal pain (48%). The patients were treated for single or co-infections using pre-packed National Aids Control Program III STI/RTI Kits. However, based on PCR diagnostics, 1453/1797 (81%) subjects were uninfected for NG/TV/CT. Amongst 344 (19%) infected patients, 257 (75%) carried infection with single pathogen (TV/NG/CT) while 87/344 (25%) were co-infected with multiple pathogens. Prevalence of TV, NG & CT was 4%, 7% and 8% respectively. Co-infection with CT + NG was highest, 51% (44/87), whereas, co-infection with CT + TV was 21% and NG + TV was 18% while co-infection with all three pathogens was 1.3%. We conclude that SCM is imprecise and successful intervention requires accurate and confirmatory diagnostic approach.Subash Chandra SonkarKirti WasnikAnita KumarVineeta SharmaPratima MittalPrashant Kumar MishraMausumi BharadwajDaman SalujaNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-9 (2017) |
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Medicine R Science Q Subash Chandra Sonkar Kirti Wasnik Anita Kumar Vineeta Sharma Pratima Mittal Prashant Kumar Mishra Mausumi Bharadwaj Daman Saluja Evaluating the utility of syndromic case management for three sexually transmitted infections in women visiting hospitals in Delhi, India |
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Abstract Utility of syndromic case management (SCM) in women visiting obstetrics & gynecology department needs to be evaluated as it is subjective and imperfect. Consequently, antibiotic resistance has accelerated along with increased risk of infection to the partners. To understand the effectiveness and/or inadequacies of SCM, 11000 women were recruited and examined by clinicians for infection by Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG), Trichomonas vaginalis (TV), Bacterial vaginosis (BV) and others. Amongst these patients, 1797 (16.3%) reported vaginal discharge (VD). Other symptoms included: vaginitis (97%), cervicitis (75%), genital ulcers (60%), abnormal vaginal discharge (55%) and lower abdominal pain (48%). The patients were treated for single or co-infections using pre-packed National Aids Control Program III STI/RTI Kits. However, based on PCR diagnostics, 1453/1797 (81%) subjects were uninfected for NG/TV/CT. Amongst 344 (19%) infected patients, 257 (75%) carried infection with single pathogen (TV/NG/CT) while 87/344 (25%) were co-infected with multiple pathogens. Prevalence of TV, NG & CT was 4%, 7% and 8% respectively. Co-infection with CT + NG was highest, 51% (44/87), whereas, co-infection with CT + TV was 21% and NG + TV was 18% while co-infection with all three pathogens was 1.3%. We conclude that SCM is imprecise and successful intervention requires accurate and confirmatory diagnostic approach. |
format |
article |
author |
Subash Chandra Sonkar Kirti Wasnik Anita Kumar Vineeta Sharma Pratima Mittal Prashant Kumar Mishra Mausumi Bharadwaj Daman Saluja |
author_facet |
Subash Chandra Sonkar Kirti Wasnik Anita Kumar Vineeta Sharma Pratima Mittal Prashant Kumar Mishra Mausumi Bharadwaj Daman Saluja |
author_sort |
Subash Chandra Sonkar |
title |
Evaluating the utility of syndromic case management for three sexually transmitted infections in women visiting hospitals in Delhi, India |
title_short |
Evaluating the utility of syndromic case management for three sexually transmitted infections in women visiting hospitals in Delhi, India |
title_full |
Evaluating the utility of syndromic case management for three sexually transmitted infections in women visiting hospitals in Delhi, India |
title_fullStr |
Evaluating the utility of syndromic case management for three sexually transmitted infections in women visiting hospitals in Delhi, India |
title_full_unstemmed |
Evaluating the utility of syndromic case management for three sexually transmitted infections in women visiting hospitals in Delhi, India |
title_sort |
evaluating the utility of syndromic case management for three sexually transmitted infections in women visiting hospitals in delhi, india |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/e7b774ef42894d9bb6db71b453002213 |
work_keys_str_mv |
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