Increased FUN14 domain containing 1 (FUNDC1) ubiquitination level inhibits mitophagy and alleviates the injury in hypoxia-induced trophoblast cells

Preeclampsia (PE) is a pregnancy disorder characterized by excessive trophoblast cell death. This study aims to explore the exact mechanism of the ubiquitination level of FUN14 domain containing 1 (FUNDC1) in mitophagy and injury in hypoxic trophoblast cells. In this study, HTR-8/SVneo trophoblast c...

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Bibliographic Details
Main Authors: GuoQing Chen, Lu Chen, Yan Huang, XiongShan Zhu, YuanLan Yu
Format: article
Language:EN
Published: Taylor & Francis Group 2021
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Online Access:https://doaj.org/article/e7b7debb99a64b45a4f2e00a99471e3c
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