Glycated hemoglobin test: diagnostic difficulties in gestational diabetes

Aims. To determine sensitivity and specificity of glycated hemoglobin (HbA1c) test with direct immunoturbidimetry as a method to diagnose gestational diabetes (GD). Materials and Methods. 74 pregnant females were recruited during initial screening. Glycemic disorders were diagnosed with two method...

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Autores principales: Tatiana Vladimirovna Saprina, Ekaterina Sergeevna Timokhina, Irina Nikolaevna Vorozhtsova
Formato: article
Lenguaje:EN
RU
Publicado: Endocrinology Research Centre 2012
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Acceso en línea:https://doaj.org/article/e7d538f343164c31b541f2012b571a09
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Sumario:Aims. To determine sensitivity and specificity of glycated hemoglobin (HbA1c) test with direct immunoturbidimetry as a method to diagnose gestational diabetes (GD). Materials and Methods. 74 pregnant females were recruited during initial screening. Glycemic disorders were diagnosed with two methods: oral glucose tolerance test with 75 g of glucose and glycated hemoglobin test. Results. HbA1c test with direct immunoturbidimetry is a highly sensitive method for diagnosis of glycemic disorders of pregnancy, provided that cut-off level is lowered to 5.5%. Conclusion. Mild anemia was not found to have a significant impact on diagnostic value of HbA1c test.