Glycated hemoglobin test: diagnostic difficulties in gestational diabetes

Aims. To determine sensitivity and specificity of glycated hemoglobin (HbA1c) test with direct immunoturbidimetry as a method to diagnose gestational diabetes (GD). Materials and Methods. 74 pregnant females were recruited during initial screening. Glycemic disorders were diagnosed with two method...

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Autores principales: Tatiana Vladimirovna Saprina, Ekaterina Sergeevna Timokhina, Irina Nikolaevna Vorozhtsova
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Lenguaje:EN
RU
Publicado: Endocrinology Research Centre 2012
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Acceso en línea:https://doaj.org/article/e7d538f343164c31b541f2012b571a09
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spelling oai:doaj.org-article:e7d538f343164c31b541f2012b571a092021-11-14T09:00:17ZGlycated hemoglobin test: diagnostic difficulties in gestational diabetes2072-03512072-037810.14341/2072-0351-5540https://doaj.org/article/e7d538f343164c31b541f2012b571a092012-12-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/5540https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Aims. To determine sensitivity and specificity of glycated hemoglobin (HbA1c) test with direct immunoturbidimetry as a method to diagnose gestational diabetes (GD). Materials and Methods. 74 pregnant females were recruited during initial screening. Glycemic disorders were diagnosed with two methods: oral glucose tolerance test with 75 g of glucose and glycated hemoglobin test. Results. HbA1c test with direct immunoturbidimetry is a highly sensitive method for diagnosis of glycemic disorders of pregnancy, provided that cut-off level is lowered to 5.5%. Conclusion. Mild anemia was not found to have a significant impact on diagnostic value of HbA1c test.Tatiana Vladimirovna SaprinaEkaterina Sergeevna TimokhinaIrina Nikolaevna VorozhtsovaEndocrinology Research Centrearticlepregnancygestational diabetesglycated hemoglobinsensitivityspecificityNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 15, Iss 4, Pp 63-68 (2012)
institution DOAJ
collection DOAJ
language EN
RU
topic pregnancy
gestational diabetes
glycated hemoglobin
sensitivity
specificity
Nutritional diseases. Deficiency diseases
RC620-627
spellingShingle pregnancy
gestational diabetes
glycated hemoglobin
sensitivity
specificity
Nutritional diseases. Deficiency diseases
RC620-627
Tatiana Vladimirovna Saprina
Ekaterina Sergeevna Timokhina
Irina Nikolaevna Vorozhtsova
Glycated hemoglobin test: diagnostic difficulties in gestational diabetes
description Aims. To determine sensitivity and specificity of glycated hemoglobin (HbA1c) test with direct immunoturbidimetry as a method to diagnose gestational diabetes (GD). Materials and Methods. 74 pregnant females were recruited during initial screening. Glycemic disorders were diagnosed with two methods: oral glucose tolerance test with 75 g of glucose and glycated hemoglobin test. Results. HbA1c test with direct immunoturbidimetry is a highly sensitive method for diagnosis of glycemic disorders of pregnancy, provided that cut-off level is lowered to 5.5%. Conclusion. Mild anemia was not found to have a significant impact on diagnostic value of HbA1c test.
format article
author Tatiana Vladimirovna Saprina
Ekaterina Sergeevna Timokhina
Irina Nikolaevna Vorozhtsova
author_facet Tatiana Vladimirovna Saprina
Ekaterina Sergeevna Timokhina
Irina Nikolaevna Vorozhtsova
author_sort Tatiana Vladimirovna Saprina
title Glycated hemoglobin test: diagnostic difficulties in gestational diabetes
title_short Glycated hemoglobin test: diagnostic difficulties in gestational diabetes
title_full Glycated hemoglobin test: diagnostic difficulties in gestational diabetes
title_fullStr Glycated hemoglobin test: diagnostic difficulties in gestational diabetes
title_full_unstemmed Glycated hemoglobin test: diagnostic difficulties in gestational diabetes
title_sort glycated hemoglobin test: diagnostic difficulties in gestational diabetes
publisher Endocrinology Research Centre
publishDate 2012
url https://doaj.org/article/e7d538f343164c31b541f2012b571a09
work_keys_str_mv AT tatianavladimirovnasaprina glycatedhemoglobintestdiagnosticdifficultiesingestationaldiabetes
AT ekaterinasergeevnatimokhina glycatedhemoglobintestdiagnosticdifficultiesingestationaldiabetes
AT irinanikolaevnavorozhtsova glycatedhemoglobintestdiagnosticdifficultiesingestationaldiabetes
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