Cardiac injury of the newborn mammalian heart accelerates cardiomyocyte terminal differentiation

Abstract After birth cardiomyocytes undergo terminal differentiation, characterized by binucleation and centrosome disassembly, rendering the heart unable to regenerate. Yet, it has been suggested that newborn mammals regenerate their hearts after apical resection by cardiomyocyte proliferation. Thu...

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Bibliographic Details
Main Authors: David C. Zebrowski, Charlotte H. Jensen, Robert Becker, Fulvia Ferrazzi, Christina Baun, Svend Hvidsten, Søren P. Sheikh, Brian D. Polizzotti, Ditte C. Andersen, Felix B. Engel
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/e7d8aee405594a0083d3e1c9ea9c1ef3
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