Crystal structure of a lipin/Pah phosphatidic acid phosphatase

Lipin/Pah phosphatidic acid phosphatases generate diacylglycerol to regulate triglyceride synthesis and cellular signaling. Here authors determine structures of Tetrahymena thermophila Pah2 and identify an N-terminal amphipathic helix essential for membrane association.

Guardado en:

Detalles Bibliográficos
Autores principales:	Valerie I. Khayyo, Reece M. Hoffmann, Huan Wang, Justin A. Bell, John E. Burke, Karen Reue, Michael V. Airola
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e7dcb21670bd4693b4f6bcddbb95ec7f
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:e7dcb21670bd4693b4f6bcddbb95ec7f
record_format	dspace
spelling	oai:doaj.org-article:e7dcb21670bd4693b4f6bcddbb95ec7f2021-12-02T16:49:27ZCrystal structure of a lipin/Pah phosphatidic acid phosphatase10.1038/s41467-020-15124-z2041-1723https://doaj.org/article/e7dcb21670bd4693b4f6bcddbb95ec7f2020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15124-zhttps://doaj.org/toc/2041-1723Lipin/Pah phosphatidic acid phosphatases generate diacylglycerol to regulate triglyceride synthesis and cellular signaling. Here authors determine structures of Tetrahymena thermophila Pah2 and identify an N-terminal amphipathic helix essential for membrane association.Valerie I. KhayyoReece M. HoffmannHuan WangJustin A. BellJohn E. BurkeKaren ReueMichael V. AirolaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Valerie I. Khayyo Reece M. Hoffmann Huan Wang Justin A. Bell John E. Burke Karen Reue Michael V. Airola Crystal structure of a lipin/Pah phosphatidic acid phosphatase
description	Lipin/Pah phosphatidic acid phosphatases generate diacylglycerol to regulate triglyceride synthesis and cellular signaling. Here authors determine structures of Tetrahymena thermophila Pah2 and identify an N-terminal amphipathic helix essential for membrane association.
format	article
author	Valerie I. Khayyo Reece M. Hoffmann Huan Wang Justin A. Bell John E. Burke Karen Reue Michael V. Airola
author_facet	Valerie I. Khayyo Reece M. Hoffmann Huan Wang Justin A. Bell John E. Burke Karen Reue Michael V. Airola
author_sort	Valerie I. Khayyo
title	Crystal structure of a lipin/Pah phosphatidic acid phosphatase
title_short	Crystal structure of a lipin/Pah phosphatidic acid phosphatase
title_full	Crystal structure of a lipin/Pah phosphatidic acid phosphatase
title_fullStr	Crystal structure of a lipin/Pah phosphatidic acid phosphatase
title_full_unstemmed	Crystal structure of a lipin/Pah phosphatidic acid phosphatase
title_sort	crystal structure of a lipin/pah phosphatidic acid phosphatase
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/e7dcb21670bd4693b4f6bcddbb95ec7f
work_keys_str_mv	AT valerieikhayyo crystalstructureofalipinpahphosphatidicacidphosphatase AT reecemhoffmann crystalstructureofalipinpahphosphatidicacidphosphatase AT huanwang crystalstructureofalipinpahphosphatidicacidphosphatase AT justinabell crystalstructureofalipinpahphosphatidicacidphosphatase AT johneburke crystalstructureofalipinpahphosphatidicacidphosphatase AT karenreue crystalstructureofalipinpahphosphatidicacidphosphatase AT michaelvairola crystalstructureofalipinpahphosphatidicacidphosphatase
_version_	1718383369853599744

Crystal structure of a lipin/Pah phosphatidic acid phosphatase

Ejemplares similares