Discovery and characterization of human exonic transcriptional regulatory elements.

Discovery and characterization of human exonic transcriptional regulatory elements.

We sought exonic transcriptional regulatory elements by shotgun cloning human cDNA fragments into luciferase reporter vectors and measuring the resulting expression levels in liver cells. We uncovered seven regulatory elements within coding regions and three within 3' untranslated regions (UTRs...

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Autores principales: Arshad H Khan, Andy Lin, Desmond J Smith
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/e7ddf6fd1694459392de2c899988137d
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