Ultrahigh-speed point scanning two-photon microscopy using high dynamic range silicon photomultipliers

Abstract Conventional two-photon microscopes use photomultiplier tubes, which enable high sensitivity but can detect relatively few photons per second, forcing longer pixel integration times and limiting maximum imaging rates. We introduce novel detection electronics using silicon photomultipliers t...

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Bibliographic Details
Main Authors: Vincent D. Ching-Roa, Eben M. Olson, Sherrif F. Ibrahim, Richard Torres, Michael G. Giacomelli
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
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Q
Online Access:https://doaj.org/article/e7deef1b6b114f769527cbff79fb3da8
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