Ten-eleven translocation 2 interacts with forkhead box O3 and regulates adult neurogenesis

Epigenetic modifications, such as DNA methylation, play an important role in adult neurogenesis. Here the authors show that Tet2, which converts 5mC to 5hmC, interacts with the transcription factor Foxo3a and regulates critical genes related to the proliferation and differentiation of adult neural s...

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Autores principales:	Xuekun Li, Bing Yao, Li Chen, Yunhee Kang, Yujing Li, Ying Cheng, Liping Li, Li Lin, Zhiqin Wang, Mengli Wang, Feng Pan, Qing Dai, Wei Zhang, Hao Wu, Qiang Shu, Zhaohui Qin, Chuan He, Mingjiang Xu, Peng Jin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e7eae03bda61408dacebbc67da52c91f
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spelling	oai:doaj.org-article:e7eae03bda61408dacebbc67da52c91f2021-12-02T15:37:02ZTen-eleven translocation 2 interacts with forkhead box O3 and regulates adult neurogenesis10.1038/ncomms159032041-1723https://doaj.org/article/e7eae03bda61408dacebbc67da52c91f2017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15903https://doaj.org/toc/2041-1723Epigenetic modifications, such as DNA methylation, play an important role in adult neurogenesis. Here the authors show that Tet2, which converts 5mC to 5hmC, interacts with the transcription factor Foxo3a and regulates critical genes related to the proliferation and differentiation of adult neural stem cells.Xuekun LiBing YaoLi ChenYunhee KangYujing LiYing ChengLiping LiLi LinZhiqin WangMengli WangFeng PanQing DaiWei ZhangHao WuQiang ShuZhaohui QinChuan HeMingjiang XuPeng JinNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xuekun Li Bing Yao Li Chen Yunhee Kang Yujing Li Ying Cheng Liping Li Li Lin Zhiqin Wang Mengli Wang Feng Pan Qing Dai Wei Zhang Hao Wu Qiang Shu Zhaohui Qin Chuan He Mingjiang Xu Peng Jin Ten-eleven translocation 2 interacts with forkhead box O3 and regulates adult neurogenesis
description	Epigenetic modifications, such as DNA methylation, play an important role in adult neurogenesis. Here the authors show that Tet2, which converts 5mC to 5hmC, interacts with the transcription factor Foxo3a and regulates critical genes related to the proliferation and differentiation of adult neural stem cells.
format	article
author	Xuekun Li Bing Yao Li Chen Yunhee Kang Yujing Li Ying Cheng Liping Li Li Lin Zhiqin Wang Mengli Wang Feng Pan Qing Dai Wei Zhang Hao Wu Qiang Shu Zhaohui Qin Chuan He Mingjiang Xu Peng Jin
author_facet	Xuekun Li Bing Yao Li Chen Yunhee Kang Yujing Li Ying Cheng Liping Li Li Lin Zhiqin Wang Mengli Wang Feng Pan Qing Dai Wei Zhang Hao Wu Qiang Shu Zhaohui Qin Chuan He Mingjiang Xu Peng Jin
author_sort	Xuekun Li
title	Ten-eleven translocation 2 interacts with forkhead box O3 and regulates adult neurogenesis
title_short	Ten-eleven translocation 2 interacts with forkhead box O3 and regulates adult neurogenesis
title_full	Ten-eleven translocation 2 interacts with forkhead box O3 and regulates adult neurogenesis
title_fullStr	Ten-eleven translocation 2 interacts with forkhead box O3 and regulates adult neurogenesis
title_full_unstemmed	Ten-eleven translocation 2 interacts with forkhead box O3 and regulates adult neurogenesis
title_sort	ten-eleven translocation 2 interacts with forkhead box o3 and regulates adult neurogenesis
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/e7eae03bda61408dacebbc67da52c91f
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Ten-eleven translocation 2 interacts with forkhead box O3 and regulates adult neurogenesis

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