Acute surgical site infection after total knee arthroplasty in patients with rheumatoid arthritis versus osteoarthritis

Abstract Osteoarthritis is the main cause for total knee arthroplasty (TKA), followed by rheumatoid arthritis. Previous studies have reported conflicting results concerning the risk of surgical site infection after TKA for rheumatoid arthritis and osteoarthritis patients. Thus, this study aimed to e...

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Autores principales:	Ho-Ken Chung, Shu-Hui Wen, Wei-Chuan Chang, Kuan-Lin Liu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/e7eedbf87bcf4fdfbd0a0a71730e3ce6
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spelling	oai:doaj.org-article:e7eedbf87bcf4fdfbd0a0a71730e3ce62021-11-28T12:18:09ZAcute surgical site infection after total knee arthroplasty in patients with rheumatoid arthritis versus osteoarthritis10.1038/s41598-021-02153-x2045-2322https://doaj.org/article/e7eedbf87bcf4fdfbd0a0a71730e3ce62021-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-02153-xhttps://doaj.org/toc/2045-2322Abstract Osteoarthritis is the main cause for total knee arthroplasty (TKA), followed by rheumatoid arthritis. Previous studies have reported conflicting results concerning the risk of surgical site infection after TKA for rheumatoid arthritis and osteoarthritis patients. Thus, this study aimed to examine whether rheumatoid arthritis patients had a higher risk of acute surgical site infection after TKA compared to osteoarthritis patients. We conducted a retrospective cohort study using Taiwan’s National Health Insurance Research Database of the whole population from 2012 to 2015, and collected the medical records of osteoarthritis patients or rheumatoid arthritis patients who underwent TKA. To evaluate the risk of acute surgical site infection in rheumatoid arthritis patients, propensity score matching was implemented for osteoarthritis patients. Acute surgical site infection was observed in 2.58% of TKA cases in rheumatoid arthritis patients and 2.66% of TKA cases in osteoarthritis patients. Rheumatoid arthritis and osteoarthritis patients had comparable risk for 90-day (odds ratio = 0.81, 95% confidence interval: 0.371–1.768) and 1-year (odds ratio = 0.463, 95% confidence interval: 0.121–1.766) surgical site infection. In conclusion, patients with rheumatoid arthritis were not at higher risk of acute surgical site infection after TKA compared to osteoarthritis patients. The current treatment strategy for patients with RA is safe and appropriate if they require TKA.Ho-Ken ChungShu-Hui WenWei-Chuan ChangKuan-Lin LiuNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Ho-Ken Chung Shu-Hui Wen Wei-Chuan Chang Kuan-Lin Liu Acute surgical site infection after total knee arthroplasty in patients with rheumatoid arthritis versus osteoarthritis
description	Abstract Osteoarthritis is the main cause for total knee arthroplasty (TKA), followed by rheumatoid arthritis. Previous studies have reported conflicting results concerning the risk of surgical site infection after TKA for rheumatoid arthritis and osteoarthritis patients. Thus, this study aimed to examine whether rheumatoid arthritis patients had a higher risk of acute surgical site infection after TKA compared to osteoarthritis patients. We conducted a retrospective cohort study using Taiwan’s National Health Insurance Research Database of the whole population from 2012 to 2015, and collected the medical records of osteoarthritis patients or rheumatoid arthritis patients who underwent TKA. To evaluate the risk of acute surgical site infection in rheumatoid arthritis patients, propensity score matching was implemented for osteoarthritis patients. Acute surgical site infection was observed in 2.58% of TKA cases in rheumatoid arthritis patients and 2.66% of TKA cases in osteoarthritis patients. Rheumatoid arthritis and osteoarthritis patients had comparable risk for 90-day (odds ratio = 0.81, 95% confidence interval: 0.371–1.768) and 1-year (odds ratio = 0.463, 95% confidence interval: 0.121–1.766) surgical site infection. In conclusion, patients with rheumatoid arthritis were not at higher risk of acute surgical site infection after TKA compared to osteoarthritis patients. The current treatment strategy for patients with RA is safe and appropriate if they require TKA.
format	article
author	Ho-Ken Chung Shu-Hui Wen Wei-Chuan Chang Kuan-Lin Liu
author_facet	Ho-Ken Chung Shu-Hui Wen Wei-Chuan Chang Kuan-Lin Liu
author_sort	Ho-Ken Chung
title	Acute surgical site infection after total knee arthroplasty in patients with rheumatoid arthritis versus osteoarthritis
title_short	Acute surgical site infection after total knee arthroplasty in patients with rheumatoid arthritis versus osteoarthritis
title_full	Acute surgical site infection after total knee arthroplasty in patients with rheumatoid arthritis versus osteoarthritis
title_fullStr	Acute surgical site infection after total knee arthroplasty in patients with rheumatoid arthritis versus osteoarthritis
title_full_unstemmed	Acute surgical site infection after total knee arthroplasty in patients with rheumatoid arthritis versus osteoarthritis
title_sort	acute surgical site infection after total knee arthroplasty in patients with rheumatoid arthritis versus osteoarthritis
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/e7eedbf87bcf4fdfbd0a0a71730e3ce6
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Acute surgical site infection after total knee arthroplasty in patients with rheumatoid arthritis versus osteoarthritis

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