Dynamic molecular changes during the first week of human life follow a robust developmental trajectory

The first week of life impacts health for all of life, but the mechanisms are little-understood. Here the authors extract multi-omic data from small volumes of blood to study the dynamic molecular changes during the first week of life, revealing a robust developmental trajectory common to different...

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Autores principales: Amy H. Lee, Casey P. Shannon, Nelly Amenyogbe, Tue B. Bennike, Joann Diray-Arce, Olubukola T. Idoko, Erin E. Gill, Rym Ben-Othman, William S. Pomat, Simon D. van Haren, Kim-Anh Lê Cao, Momoudou Cox, Alansana Darboe, Reza Falsafi, Davide Ferrari, Daniel J. Harbeson, Daniel He, Cai Bing, Samuel J. Hinshaw, Jorjoh Ndure, Jainaba Njie-Jobe, Matthew A. Pettengill, Peter C. Richmond, Rebecca Ford, Gerard Saleu, Geraldine Masiria, John Paul Matlam, Wendy Kirarock, Elishia Roberts, Mehrnoush Malek, Guzmán Sanchez-Schmitz, Amrit Singh, Asimenia Angelidou, Kinga K. Smolen, The EPIC Consortium, Ryan R. Brinkman, Al Ozonoff, Robert E. W. Hancock, Anita H. J. van den Biggelaar, Hanno Steen, Scott J. Tebbutt, Beate Kampmann, Ofer Levy, Tobias R. Kollmann
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Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/e7ef77b9e7334ea3b111c65372e1f94f
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spelling oai:doaj.org-article:e7ef77b9e7334ea3b111c65372e1f94f2021-12-02T14:38:39ZDynamic molecular changes during the first week of human life follow a robust developmental trajectory10.1038/s41467-019-08794-x2041-1723https://doaj.org/article/e7ef77b9e7334ea3b111c65372e1f94f2019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08794-xhttps://doaj.org/toc/2041-1723The first week of life impacts health for all of life, but the mechanisms are little-understood. Here the authors extract multi-omic data from small volumes of blood to study the dynamic molecular changes during the first week of life, revealing a robust developmental trajectory common to different populations.Amy H. LeeCasey P. ShannonNelly AmenyogbeTue B. BennikeJoann Diray-ArceOlubukola T. IdokoErin E. GillRym Ben-OthmanWilliam S. PomatSimon D. van HarenKim-Anh Lê CaoMomoudou CoxAlansana DarboeReza FalsafiDavide FerrariDaniel J. HarbesonDaniel HeCai BingSamuel J. HinshawJorjoh NdureJainaba Njie-JobeMatthew A. PettengillPeter C. RichmondRebecca FordGerard SaleuGeraldine MasiriaJohn Paul MatlamWendy KirarockElishia RobertsMehrnoush MalekGuzmán Sanchez-SchmitzAmrit SinghAsimenia AngelidouKinga K. SmolenThe EPIC ConsortiumRyan R. BrinkmanAl OzonoffRobert E. W. HancockAnita H. J. van den BiggelaarHanno SteenScott J. TebbuttBeate KampmannOfer LevyTobias R. KollmannNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Amy H. Lee
Casey P. Shannon
Nelly Amenyogbe
Tue B. Bennike
Joann Diray-Arce
Olubukola T. Idoko
Erin E. Gill
Rym Ben-Othman
William S. Pomat
Simon D. van Haren
Kim-Anh Lê Cao
Momoudou Cox
Alansana Darboe
Reza Falsafi
Davide Ferrari
Daniel J. Harbeson
Daniel He
Cai Bing
Samuel J. Hinshaw
Jorjoh Ndure
Jainaba Njie-Jobe
Matthew A. Pettengill
Peter C. Richmond
Rebecca Ford
Gerard Saleu
Geraldine Masiria
John Paul Matlam
Wendy Kirarock
Elishia Roberts
Mehrnoush Malek
Guzmán Sanchez-Schmitz
Amrit Singh
Asimenia Angelidou
Kinga K. Smolen
The EPIC Consortium
Ryan R. Brinkman
Al Ozonoff
Robert E. W. Hancock
Anita H. J. van den Biggelaar
Hanno Steen
Scott J. Tebbutt
Beate Kampmann
Ofer Levy
Tobias R. Kollmann
Dynamic molecular changes during the first week of human life follow a robust developmental trajectory
description The first week of life impacts health for all of life, but the mechanisms are little-understood. Here the authors extract multi-omic data from small volumes of blood to study the dynamic molecular changes during the first week of life, revealing a robust developmental trajectory common to different populations.
format article
author Amy H. Lee
Casey P. Shannon
Nelly Amenyogbe
Tue B. Bennike
Joann Diray-Arce
Olubukola T. Idoko
Erin E. Gill
Rym Ben-Othman
William S. Pomat
Simon D. van Haren
Kim-Anh Lê Cao
Momoudou Cox
Alansana Darboe
Reza Falsafi
Davide Ferrari
Daniel J. Harbeson
Daniel He
Cai Bing
Samuel J. Hinshaw
Jorjoh Ndure
Jainaba Njie-Jobe
Matthew A. Pettengill
Peter C. Richmond
Rebecca Ford
Gerard Saleu
Geraldine Masiria
John Paul Matlam
Wendy Kirarock
Elishia Roberts
Mehrnoush Malek
Guzmán Sanchez-Schmitz
Amrit Singh
Asimenia Angelidou
Kinga K. Smolen
The EPIC Consortium
Ryan R. Brinkman
Al Ozonoff
Robert E. W. Hancock
Anita H. J. van den Biggelaar
Hanno Steen
Scott J. Tebbutt
Beate Kampmann
Ofer Levy
Tobias R. Kollmann
author_facet Amy H. Lee
Casey P. Shannon
Nelly Amenyogbe
Tue B. Bennike
Joann Diray-Arce
Olubukola T. Idoko
Erin E. Gill
Rym Ben-Othman
William S. Pomat
Simon D. van Haren
Kim-Anh Lê Cao
Momoudou Cox
Alansana Darboe
Reza Falsafi
Davide Ferrari
Daniel J. Harbeson
Daniel He
Cai Bing
Samuel J. Hinshaw
Jorjoh Ndure
Jainaba Njie-Jobe
Matthew A. Pettengill
Peter C. Richmond
Rebecca Ford
Gerard Saleu
Geraldine Masiria
John Paul Matlam
Wendy Kirarock
Elishia Roberts
Mehrnoush Malek
Guzmán Sanchez-Schmitz
Amrit Singh
Asimenia Angelidou
Kinga K. Smolen
The EPIC Consortium
Ryan R. Brinkman
Al Ozonoff
Robert E. W. Hancock
Anita H. J. van den Biggelaar
Hanno Steen
Scott J. Tebbutt
Beate Kampmann
Ofer Levy
Tobias R. Kollmann
author_sort Amy H. Lee
title Dynamic molecular changes during the first week of human life follow a robust developmental trajectory
title_short Dynamic molecular changes during the first week of human life follow a robust developmental trajectory
title_full Dynamic molecular changes during the first week of human life follow a robust developmental trajectory
title_fullStr Dynamic molecular changes during the first week of human life follow a robust developmental trajectory
title_full_unstemmed Dynamic molecular changes during the first week of human life follow a robust developmental trajectory
title_sort dynamic molecular changes during the first week of human life follow a robust developmental trajectory
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/e7ef77b9e7334ea3b111c65372e1f94f
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