An anaerobic bacterium host system for heterologous expression of natural product biosynthetic gene clusters
Anaerobic bacteria represent a rich source of biological and chemical diversity but are difficult to cultivate and there is a lack of heterologous expression systems. Here the authors develop an expression system based on S. mutans UA159 for biosynthetic gene clusters from anaerobic bacteria.
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Nature Portfolio
2019
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oai:doaj.org-article:e7f2bd25d9b24d798c21096cacfced892021-12-02T14:35:30ZAn anaerobic bacterium host system for heterologous expression of natural product biosynthetic gene clusters10.1038/s41467-019-11673-02041-1723https://doaj.org/article/e7f2bd25d9b24d798c21096cacfced892019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11673-0https://doaj.org/toc/2041-1723Anaerobic bacteria represent a rich source of biological and chemical diversity but are difficult to cultivate and there is a lack of heterologous expression systems. Here the authors develop an expression system based on S. mutans UA159 for biosynthetic gene clusters from anaerobic bacteria.Tingting HaoZhoujie XieMin WangLiwei LiuYuwei ZhangWeicang WangZhao ZhangXuejin ZhaoPengwei LiZhengyan GuoShushan GaoChunbo LouGuodong ZhangJustin MerrittGeoff P. HorsmanYihua ChenNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Tingting Hao Zhoujie Xie Min Wang Liwei Liu Yuwei Zhang Weicang Wang Zhao Zhang Xuejin Zhao Pengwei Li Zhengyan Guo Shushan Gao Chunbo Lou Guodong Zhang Justin Merritt Geoff P. Horsman Yihua Chen An anaerobic bacterium host system for heterologous expression of natural product biosynthetic gene clusters |
| description |
Anaerobic bacteria represent a rich source of biological and chemical diversity but are difficult to cultivate and there is a lack of heterologous expression systems. Here the authors develop an expression system based on S. mutans UA159 for biosynthetic gene clusters from anaerobic bacteria. |
| format |
article |
| author |
Tingting Hao Zhoujie Xie Min Wang Liwei Liu Yuwei Zhang Weicang Wang Zhao Zhang Xuejin Zhao Pengwei Li Zhengyan Guo Shushan Gao Chunbo Lou Guodong Zhang Justin Merritt Geoff P. Horsman Yihua Chen |
| author_facet |
Tingting Hao Zhoujie Xie Min Wang Liwei Liu Yuwei Zhang Weicang Wang Zhao Zhang Xuejin Zhao Pengwei Li Zhengyan Guo Shushan Gao Chunbo Lou Guodong Zhang Justin Merritt Geoff P. Horsman Yihua Chen |
| author_sort |
Tingting Hao |
| title |
An anaerobic bacterium host system for heterologous expression of natural product biosynthetic gene clusters |
| title_short |
An anaerobic bacterium host system for heterologous expression of natural product biosynthetic gene clusters |
| title_full |
An anaerobic bacterium host system for heterologous expression of natural product biosynthetic gene clusters |
| title_fullStr |
An anaerobic bacterium host system for heterologous expression of natural product biosynthetic gene clusters |
| title_full_unstemmed |
An anaerobic bacterium host system for heterologous expression of natural product biosynthetic gene clusters |
| title_sort |
anaerobic bacterium host system for heterologous expression of natural product biosynthetic gene clusters |
| publisher |
Nature Portfolio |
| publishDate |
2019 |
| url |
https://doaj.org/article/e7f2bd25d9b24d798c21096cacfced89 |
| work_keys_str_mv |
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