Mechanism of intermediate filament recognition by plakin repeat domains revealed by envoplakin targeting of vimentin

Plakin proteins link cell junctions to cytoskeletal frameworks, and their disruption within epithelial and cardiac muscle cells cause skin blistering diseases and cardiomyopathies. Here the authors use structural biology approaches to reveal the mechanism that allows plakins to recognize intermediat...

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Autores principales:	Claudia Fogl, Fiyaz Mohammed, Caezar Al-Jassar, Mark Jeeves, Timothy J. Knowles, Penelope Rodriguez-Zamora, Scott A. White, Elena Odintsova, Michael Overduin, Martyn Chidgey
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e7f4b72653954877a76e2efd1c2dacdd
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spelling	oai:doaj.org-article:e7f4b72653954877a76e2efd1c2dacdd2021-12-02T14:39:34ZMechanism of intermediate filament recognition by plakin repeat domains revealed by envoplakin targeting of vimentin10.1038/ncomms108272041-1723https://doaj.org/article/e7f4b72653954877a76e2efd1c2dacdd2016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms10827https://doaj.org/toc/2041-1723Plakin proteins link cell junctions to cytoskeletal frameworks, and their disruption within epithelial and cardiac muscle cells cause skin blistering diseases and cardiomyopathies. Here the authors use structural biology approaches to reveal the mechanism that allows plakins to recognize intermediate filaments within the cytoskeleton.Claudia FoglFiyaz MohammedCaezar Al-JassarMark JeevesTimothy J. KnowlesPenelope Rodriguez-ZamoraScott A. WhiteElena OdintsovaMichael OverduinMartyn ChidgeyNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Claudia Fogl Fiyaz Mohammed Caezar Al-Jassar Mark Jeeves Timothy J. Knowles Penelope Rodriguez-Zamora Scott A. White Elena Odintsova Michael Overduin Martyn Chidgey Mechanism of intermediate filament recognition by plakin repeat domains revealed by envoplakin targeting of vimentin
description	Plakin proteins link cell junctions to cytoskeletal frameworks, and their disruption within epithelial and cardiac muscle cells cause skin blistering diseases and cardiomyopathies. Here the authors use structural biology approaches to reveal the mechanism that allows plakins to recognize intermediate filaments within the cytoskeleton.
format	article
author	Claudia Fogl Fiyaz Mohammed Caezar Al-Jassar Mark Jeeves Timothy J. Knowles Penelope Rodriguez-Zamora Scott A. White Elena Odintsova Michael Overduin Martyn Chidgey
author_facet	Claudia Fogl Fiyaz Mohammed Caezar Al-Jassar Mark Jeeves Timothy J. Knowles Penelope Rodriguez-Zamora Scott A. White Elena Odintsova Michael Overduin Martyn Chidgey
author_sort	Claudia Fogl
title	Mechanism of intermediate filament recognition by plakin repeat domains revealed by envoplakin targeting of vimentin
title_short	Mechanism of intermediate filament recognition by plakin repeat domains revealed by envoplakin targeting of vimentin
title_full	Mechanism of intermediate filament recognition by plakin repeat domains revealed by envoplakin targeting of vimentin
title_fullStr	Mechanism of intermediate filament recognition by plakin repeat domains revealed by envoplakin targeting of vimentin
title_full_unstemmed	Mechanism of intermediate filament recognition by plakin repeat domains revealed by envoplakin targeting of vimentin
title_sort	mechanism of intermediate filament recognition by plakin repeat domains revealed by envoplakin targeting of vimentin
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/e7f4b72653954877a76e2efd1c2dacdd
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Mechanism of intermediate filament recognition by plakin repeat domains revealed by envoplakin targeting of vimentin

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