Measuring the effects of particle orientation to improve the efficiency of electron cryomicroscopy

A number of parameters influence the resolution of a cryo-EM structure. Here the authors investigate the effects of specimen orientation in single particle cryo-EM and present open-source software for rapidly assessing orientation distributions to improve data collection.

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Detalles Bibliográficos
Autores principales: Katerina Naydenova, Christopher J. Russo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/e7fc8c59bb4b44a4bf246510f6cb7c7f
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Sumario:A number of parameters influence the resolution of a cryo-EM structure. Here the authors investigate the effects of specimen orientation in single particle cryo-EM and present open-source software for rapidly assessing orientation distributions to improve data collection.