Measuring the effects of particle orientation to improve the efficiency of electron cryomicroscopy

A number of parameters influence the resolution of a cryo-EM structure. Here the authors investigate the effects of specimen orientation in single particle cryo-EM and present open-source software for rapidly assessing orientation distributions to improve data collection.

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Autores principales: Katerina Naydenova, Christopher J. Russo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/e7fc8c59bb4b44a4bf246510f6cb7c7f
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spelling oai:doaj.org-article:e7fc8c59bb4b44a4bf246510f6cb7c7f2021-12-02T14:42:04ZMeasuring the effects of particle orientation to improve the efficiency of electron cryomicroscopy10.1038/s41467-017-00782-32041-1723https://doaj.org/article/e7fc8c59bb4b44a4bf246510f6cb7c7f2017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00782-3https://doaj.org/toc/2041-1723A number of parameters influence the resolution of a cryo-EM structure. Here the authors investigate the effects of specimen orientation in single particle cryo-EM and present open-source software for rapidly assessing orientation distributions to improve data collection.Katerina NaydenovaChristopher J. RussoNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-5 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Katerina Naydenova
Christopher J. Russo
Measuring the effects of particle orientation to improve the efficiency of electron cryomicroscopy
description A number of parameters influence the resolution of a cryo-EM structure. Here the authors investigate the effects of specimen orientation in single particle cryo-EM and present open-source software for rapidly assessing orientation distributions to improve data collection.
format article
author Katerina Naydenova
Christopher J. Russo
author_facet Katerina Naydenova
Christopher J. Russo
author_sort Katerina Naydenova
title Measuring the effects of particle orientation to improve the efficiency of electron cryomicroscopy
title_short Measuring the effects of particle orientation to improve the efficiency of electron cryomicroscopy
title_full Measuring the effects of particle orientation to improve the efficiency of electron cryomicroscopy
title_fullStr Measuring the effects of particle orientation to improve the efficiency of electron cryomicroscopy
title_full_unstemmed Measuring the effects of particle orientation to improve the efficiency of electron cryomicroscopy
title_sort measuring the effects of particle orientation to improve the efficiency of electron cryomicroscopy
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/e7fc8c59bb4b44a4bf246510f6cb7c7f
work_keys_str_mv AT katerinanaydenova measuringtheeffectsofparticleorientationtoimprovetheefficiencyofelectroncryomicroscopy
AT christopherjrusso measuringtheeffectsofparticleorientationtoimprovetheefficiencyofelectroncryomicroscopy
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