Clonal dynamics in osteosarcoma defined by RGB marking

Osteosarcoma is a heterogeneous bone tumour with a high mutational rate. Here the authors use an RGB-based single-cell tracking system to track clonal dynamics in a mouse model of osteosarcoma, which their findings indicate follows a neutral evolution model in which different clones simultaneously c...

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Autores principales: Stefano Gambera, Ander Abarrategi, Fernando González-Camacho, Álvaro Morales-Molina, Josep Roma, Arantzazu Alfranca, Javier García-Castro
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/e807f4b3ffa644a8a8fcdb65236ade01
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spelling oai:doaj.org-article:e807f4b3ffa644a8a8fcdb65236ade012021-12-02T15:34:27ZClonal dynamics in osteosarcoma defined by RGB marking10.1038/s41467-018-06401-z2041-1723https://doaj.org/article/e807f4b3ffa644a8a8fcdb65236ade012018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06401-zhttps://doaj.org/toc/2041-1723Osteosarcoma is a heterogeneous bone tumour with a high mutational rate. Here the authors use an RGB-based single-cell tracking system to track clonal dynamics in a mouse model of osteosarcoma, which their findings indicate follows a neutral evolution model in which different clones simultaneously coexist and propagate.Stefano GamberaAnder AbarrategiFernando González-CamachoÁlvaro Morales-MolinaJosep RomaArantzazu AlfrancaJavier García-CastroNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Stefano Gambera
Ander Abarrategi
Fernando González-Camacho
Álvaro Morales-Molina
Josep Roma
Arantzazu Alfranca
Javier García-Castro
Clonal dynamics in osteosarcoma defined by RGB marking
description Osteosarcoma is a heterogeneous bone tumour with a high mutational rate. Here the authors use an RGB-based single-cell tracking system to track clonal dynamics in a mouse model of osteosarcoma, which their findings indicate follows a neutral evolution model in which different clones simultaneously coexist and propagate.
format article
author Stefano Gambera
Ander Abarrategi
Fernando González-Camacho
Álvaro Morales-Molina
Josep Roma
Arantzazu Alfranca
Javier García-Castro
author_facet Stefano Gambera
Ander Abarrategi
Fernando González-Camacho
Álvaro Morales-Molina
Josep Roma
Arantzazu Alfranca
Javier García-Castro
author_sort Stefano Gambera
title Clonal dynamics in osteosarcoma defined by RGB marking
title_short Clonal dynamics in osteosarcoma defined by RGB marking
title_full Clonal dynamics in osteosarcoma defined by RGB marking
title_fullStr Clonal dynamics in osteosarcoma defined by RGB marking
title_full_unstemmed Clonal dynamics in osteosarcoma defined by RGB marking
title_sort clonal dynamics in osteosarcoma defined by rgb marking
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/e807f4b3ffa644a8a8fcdb65236ade01
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AT alvaromoralesmolina clonaldynamicsinosteosarcomadefinedbyrgbmarking
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AT arantzazualfranca clonaldynamicsinosteosarcomadefinedbyrgbmarking
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