Clonal dynamics in osteosarcoma defined by RGB marking
Osteosarcoma is a heterogeneous bone tumour with a high mutational rate. Here the authors use an RGB-based single-cell tracking system to track clonal dynamics in a mouse model of osteosarcoma, which their findings indicate follows a neutral evolution model in which different clones simultaneously c...
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Nature Portfolio
2018
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oai:doaj.org-article:e807f4b3ffa644a8a8fcdb65236ade012021-12-02T15:34:27ZClonal dynamics in osteosarcoma defined by RGB marking10.1038/s41467-018-06401-z2041-1723https://doaj.org/article/e807f4b3ffa644a8a8fcdb65236ade012018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06401-zhttps://doaj.org/toc/2041-1723Osteosarcoma is a heterogeneous bone tumour with a high mutational rate. Here the authors use an RGB-based single-cell tracking system to track clonal dynamics in a mouse model of osteosarcoma, which their findings indicate follows a neutral evolution model in which different clones simultaneously coexist and propagate.Stefano GamberaAnder AbarrategiFernando González-CamachoÁlvaro Morales-MolinaJosep RomaArantzazu AlfrancaJavier García-CastroNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018) |
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Science Q Stefano Gambera Ander Abarrategi Fernando González-Camacho Álvaro Morales-Molina Josep Roma Arantzazu Alfranca Javier García-Castro Clonal dynamics in osteosarcoma defined by RGB marking |
description |
Osteosarcoma is a heterogeneous bone tumour with a high mutational rate. Here the authors use an RGB-based single-cell tracking system to track clonal dynamics in a mouse model of osteosarcoma, which their findings indicate follows a neutral evolution model in which different clones simultaneously coexist and propagate. |
format |
article |
author |
Stefano Gambera Ander Abarrategi Fernando González-Camacho Álvaro Morales-Molina Josep Roma Arantzazu Alfranca Javier García-Castro |
author_facet |
Stefano Gambera Ander Abarrategi Fernando González-Camacho Álvaro Morales-Molina Josep Roma Arantzazu Alfranca Javier García-Castro |
author_sort |
Stefano Gambera |
title |
Clonal dynamics in osteosarcoma defined by RGB marking |
title_short |
Clonal dynamics in osteosarcoma defined by RGB marking |
title_full |
Clonal dynamics in osteosarcoma defined by RGB marking |
title_fullStr |
Clonal dynamics in osteosarcoma defined by RGB marking |
title_full_unstemmed |
Clonal dynamics in osteosarcoma defined by RGB marking |
title_sort |
clonal dynamics in osteosarcoma defined by rgb marking |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/e807f4b3ffa644a8a8fcdb65236ade01 |
work_keys_str_mv |
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1718386873104072704 |