STUDY THE EFFECT OF ADENOSINE DEAMINASE ENZYME IN INDUCES CYTOGENETIC AND HISTOPATHOLOGICAL CHANGES IN RATS SKIN AND EYES TREATED WITH SUMICIDIN
The present investigation aimed to study the Adenosine Deaminase activity in induction Cytogentic and histopathological change in skin and eyes of sumicidine treated rats. The study Included. 1-Adenosine deaminase activity . 2-Total serum protein. 3-Micronuclei in binucleated cell. 4-Histopathologi...
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University of Baghdad, College of Veterinary Medicine
2000
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oai:doaj.org-article:e8167bdb4ac3441dbe1769acd28a8b552021-11-09T11:36:42ZSTUDY THE EFFECT OF ADENOSINE DEAMINASE ENZYME IN INDUCES CYTOGENETIC AND HISTOPATHOLOGICAL CHANGES IN RATS SKIN AND EYES TREATED WITH SUMICIDIN10.30539/ijvm.v24i2.11691609-56932410-7409https://doaj.org/article/e8167bdb4ac3441dbe1769acd28a8b552000-12-01T00:00:00Zhttps://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/1169https://doaj.org/toc/1609-5693https://doaj.org/toc/2410-7409 The present investigation aimed to study the Adenosine Deaminase activity in induction Cytogentic and histopathological change in skin and eyes of sumicidine treated rats. The study Included. 1-Adenosine deaminase activity . 2-Total serum protein. 3-Micronuclei in binucleated cell. 4-Histopathological changes in skin and eyes. 19 white male rats were used . They are randomly allocated into 3 groups : 1st group was fed 2% sumicidine for 15 days. 2nd group was fed 2% heating sumicidine for 15 days . 3rd group was kept on normal diet. Blood Adenosine Deaminase activity and Total serum protein in 1 and 2 group significantly decreased at 15 and 30 days of treated. The results indicated that sumicidine increased significantly micronucleus in group 1 and 2. Multifocal granulomatous lesions in skin & eyes of group 1 and 2 were found characterized by highly aggregation of cells (Lymphocytes, Macrophages, Foreign body giant cells and fibroblasts). In conclusion , Sumicidine even heated accompaying in decreased in decreased Adenosine Deaminase activity and total serum protein , in part a possible factor in the cytogenetic effect and accompanying granuloma formation in skin and eye . Bushra Ibrahim Al-QaisiUniversity of Baghdad, College of Veterinary MedicinearticleADENOSINEENZYMECYTOGENETICHISTOPATHOLOGICALRATSSUMICIDINVeterinary medicineSF600-1100ENThe Iraqi Journal of Veterinary Medicine, Vol 24, Iss 2 (2000) |
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DOAJ |
language |
EN |
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ADENOSINE ENZYME CYTOGENETIC HISTOPATHOLOGICAL RATS SUMICIDIN Veterinary medicine SF600-1100 |
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ADENOSINE ENZYME CYTOGENETIC HISTOPATHOLOGICAL RATS SUMICIDIN Veterinary medicine SF600-1100 Bushra Ibrahim Al-Qaisi STUDY THE EFFECT OF ADENOSINE DEAMINASE ENZYME IN INDUCES CYTOGENETIC AND HISTOPATHOLOGICAL CHANGES IN RATS SKIN AND EYES TREATED WITH SUMICIDIN |
description |
The present investigation aimed to study the Adenosine Deaminase activity in induction Cytogentic and histopathological change in skin and eyes of sumicidine treated rats. The study Included. 1-Adenosine deaminase activity . 2-Total serum protein. 3-Micronuclei in binucleated cell. 4-Histopathological changes in skin and eyes.
19 white male rats were used . They are randomly allocated into 3 groups : 1st group was fed 2% sumicidine for 15 days. 2nd group was fed 2% heating sumicidine for 15 days . 3rd group was kept on normal diet. Blood Adenosine Deaminase activity and Total serum protein in 1 and 2 group significantly decreased at 15 and 30 days of treated. The results
indicated that sumicidine increased significantly micronucleus in group 1 and 2. Multifocal granulomatous lesions in skin & eyes of group 1 and 2 were found characterized by highly aggregation of cells (Lymphocytes, Macrophages, Foreign body giant cells and fibroblasts).
In conclusion , Sumicidine even heated accompaying in decreased in decreased Adenosine Deaminase activity and total serum protein , in part a possible factor in the cytogenetic effect and accompanying granuloma formation in skin and eye .
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format |
article |
author |
Bushra Ibrahim Al-Qaisi |
author_facet |
Bushra Ibrahim Al-Qaisi |
author_sort |
Bushra Ibrahim Al-Qaisi |
title |
STUDY THE EFFECT OF ADENOSINE DEAMINASE ENZYME IN INDUCES CYTOGENETIC AND HISTOPATHOLOGICAL CHANGES IN RATS SKIN AND EYES TREATED WITH SUMICIDIN |
title_short |
STUDY THE EFFECT OF ADENOSINE DEAMINASE ENZYME IN INDUCES CYTOGENETIC AND HISTOPATHOLOGICAL CHANGES IN RATS SKIN AND EYES TREATED WITH SUMICIDIN |
title_full |
STUDY THE EFFECT OF ADENOSINE DEAMINASE ENZYME IN INDUCES CYTOGENETIC AND HISTOPATHOLOGICAL CHANGES IN RATS SKIN AND EYES TREATED WITH SUMICIDIN |
title_fullStr |
STUDY THE EFFECT OF ADENOSINE DEAMINASE ENZYME IN INDUCES CYTOGENETIC AND HISTOPATHOLOGICAL CHANGES IN RATS SKIN AND EYES TREATED WITH SUMICIDIN |
title_full_unstemmed |
STUDY THE EFFECT OF ADENOSINE DEAMINASE ENZYME IN INDUCES CYTOGENETIC AND HISTOPATHOLOGICAL CHANGES IN RATS SKIN AND EYES TREATED WITH SUMICIDIN |
title_sort |
study the effect of adenosine deaminase enzyme in induces cytogenetic and histopathological changes in rats skin and eyes treated with sumicidin |
publisher |
University of Baghdad, College of Veterinary Medicine |
publishDate |
2000 |
url |
https://doaj.org/article/e8167bdb4ac3441dbe1769acd28a8b55 |
work_keys_str_mv |
AT bushraibrahimalqaisi studytheeffectofadenosinedeaminaseenzymeininducescytogeneticandhistopathologicalchangesinratsskinandeyestreatedwithsumicidin |
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1718441162537172992 |