STUDY THE EFFECT OF ADENOSINE DEAMINASE ENZYME IN INDUCES CYTOGENETIC AND HISTOPATHOLOGICAL CHANGES IN RATS SKIN AND EYES TREATED WITH SUMICIDIN

The present investigation aimed to study the Adenosine Deaminase activity in induction Cytogentic and histopathological change in skin and eyes of sumicidine treated rats. The study Included. 1-Adenosine deaminase activity . 2-Total serum protein. 3-Micronuclei in binucleated cell. 4-Histopathologi...

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Autor principal: Bushra Ibrahim Al-Qaisi
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Lenguaje:EN
Publicado: University of Baghdad, College of Veterinary Medicine 2000
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Acceso en línea:https://doaj.org/article/e8167bdb4ac3441dbe1769acd28a8b55
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spelling oai:doaj.org-article:e8167bdb4ac3441dbe1769acd28a8b552021-11-09T11:36:42ZSTUDY THE EFFECT OF ADENOSINE DEAMINASE ENZYME IN INDUCES CYTOGENETIC AND HISTOPATHOLOGICAL CHANGES IN RATS SKIN AND EYES TREATED WITH SUMICIDIN10.30539/ijvm.v24i2.11691609-56932410-7409https://doaj.org/article/e8167bdb4ac3441dbe1769acd28a8b552000-12-01T00:00:00Zhttps://jcovm.uobaghdad.edu.iq/index.php/Iraqijvm/article/view/1169https://doaj.org/toc/1609-5693https://doaj.org/toc/2410-7409 The present investigation aimed to study the Adenosine Deaminase activity in induction Cytogentic and histopathological change in skin and eyes of sumicidine treated rats. The study Included. 1-Adenosine deaminase activity . 2-Total serum protein. 3-Micronuclei in binucleated cell. 4-Histopathological changes in skin and eyes.  19 white male rats were used . They are randomly allocated into 3 groups : 1st group was fed 2% sumicidine for 15 days. 2nd group was fed 2% heating sumicidine for 15 days . 3rd group was kept on normal diet. Blood Adenosine Deaminase activity and Total serum protein in 1 and 2 group significantly decreased at 15 and 30 days of treated. The results  indicated that sumicidine increased significantly micronucleus in group 1 and 2. Multifocal granulomatous lesions in skin & eyes of group 1 and 2 were found characterized by highly aggregation of cells (Lymphocytes, Macrophages, Foreign body giant cells and fibroblasts).  In conclusion , Sumicidine even heated accompaying in decreased in decreased Adenosine Deaminase activity and total serum protein , in part a possible factor in the cytogenetic effect and accompanying granuloma formation in skin and eye .  Bushra Ibrahim Al-QaisiUniversity of Baghdad, College of Veterinary MedicinearticleADENOSINEENZYMECYTOGENETICHISTOPATHOLOGICALRATSSUMICIDINVeterinary medicineSF600-1100ENThe Iraqi Journal of Veterinary Medicine, Vol 24, Iss 2 (2000)
institution DOAJ
collection DOAJ
language EN
topic ADENOSINE
ENZYME
CYTOGENETIC
HISTOPATHOLOGICAL
RATS
SUMICIDIN
Veterinary medicine
SF600-1100
spellingShingle ADENOSINE
ENZYME
CYTOGENETIC
HISTOPATHOLOGICAL
RATS
SUMICIDIN
Veterinary medicine
SF600-1100
Bushra Ibrahim Al-Qaisi
STUDY THE EFFECT OF ADENOSINE DEAMINASE ENZYME IN INDUCES CYTOGENETIC AND HISTOPATHOLOGICAL CHANGES IN RATS SKIN AND EYES TREATED WITH SUMICIDIN
description The present investigation aimed to study the Adenosine Deaminase activity in induction Cytogentic and histopathological change in skin and eyes of sumicidine treated rats. The study Included. 1-Adenosine deaminase activity . 2-Total serum protein. 3-Micronuclei in binucleated cell. 4-Histopathological changes in skin and eyes.  19 white male rats were used . They are randomly allocated into 3 groups : 1st group was fed 2% sumicidine for 15 days. 2nd group was fed 2% heating sumicidine for 15 days . 3rd group was kept on normal diet. Blood Adenosine Deaminase activity and Total serum protein in 1 and 2 group significantly decreased at 15 and 30 days of treated. The results  indicated that sumicidine increased significantly micronucleus in group 1 and 2. Multifocal granulomatous lesions in skin & eyes of group 1 and 2 were found characterized by highly aggregation of cells (Lymphocytes, Macrophages, Foreign body giant cells and fibroblasts).  In conclusion , Sumicidine even heated accompaying in decreased in decreased Adenosine Deaminase activity and total serum protein , in part a possible factor in the cytogenetic effect and accompanying granuloma formation in skin and eye . 
format article
author Bushra Ibrahim Al-Qaisi
author_facet Bushra Ibrahim Al-Qaisi
author_sort Bushra Ibrahim Al-Qaisi
title STUDY THE EFFECT OF ADENOSINE DEAMINASE ENZYME IN INDUCES CYTOGENETIC AND HISTOPATHOLOGICAL CHANGES IN RATS SKIN AND EYES TREATED WITH SUMICIDIN
title_short STUDY THE EFFECT OF ADENOSINE DEAMINASE ENZYME IN INDUCES CYTOGENETIC AND HISTOPATHOLOGICAL CHANGES IN RATS SKIN AND EYES TREATED WITH SUMICIDIN
title_full STUDY THE EFFECT OF ADENOSINE DEAMINASE ENZYME IN INDUCES CYTOGENETIC AND HISTOPATHOLOGICAL CHANGES IN RATS SKIN AND EYES TREATED WITH SUMICIDIN
title_fullStr STUDY THE EFFECT OF ADENOSINE DEAMINASE ENZYME IN INDUCES CYTOGENETIC AND HISTOPATHOLOGICAL CHANGES IN RATS SKIN AND EYES TREATED WITH SUMICIDIN
title_full_unstemmed STUDY THE EFFECT OF ADENOSINE DEAMINASE ENZYME IN INDUCES CYTOGENETIC AND HISTOPATHOLOGICAL CHANGES IN RATS SKIN AND EYES TREATED WITH SUMICIDIN
title_sort study the effect of adenosine deaminase enzyme in induces cytogenetic and histopathological changes in rats skin and eyes treated with sumicidin
publisher University of Baghdad, College of Veterinary Medicine
publishDate 2000
url https://doaj.org/article/e8167bdb4ac3441dbe1769acd28a8b55
work_keys_str_mv AT bushraibrahimalqaisi studytheeffectofadenosinedeaminaseenzymeininducescytogeneticandhistopathologicalchangesinratsskinandeyestreatedwithsumicidin
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