Potassium channels Kv1.3 and KCa3.1 cooperatively and compensatorily regulate antigen-specific memory T cell functions

Potassium channels Kv1.3 and KCa3.1 cooperatively and compensatorily regulate antigen-specific memory T cell functions

Potassium channels are essential for modulating T-cell functions. Here, by characterizing rat models and analysing human T cells, the authors identify differential requirements of two potassium channel proteins, Kv1.3 and KCa3.1, for the induction of conventional versus autoreactive T-cell responses...

Full description

Saved in:
Bibliographic Details
Main Authors: Eugene Y. Chiang, Tianbo Li, Surinder Jeet, Ivan Peng, Juan Zhang, Wyne P. Lee, Jason DeVoss, Patrick Caplazi, Jun Chen, Søren Warming, David H. Hackos, Susmith Mukund, Christopher M. Koth, Jane L. Grogan
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Science
Q
Online Access:https://doaj.org/article/e81be3fdce5148d7897e24bc26448b4f
Tags: Add Tag
No Tags, Be the first to tag this record!
Be the first to leave a comment!
You must be logged in first

Similar Items