De novo genic mutations among a Chinese autism spectrum disorder cohort

Recurrent sporadic mutations are important risk factors for autism spectrum disorders (ASDs) but have been primarily investigated in European cohorts. Here, Eichler, Xia and colleagues analyse risk genes in a large Chinese ASD cohort and find novel recurrences of potential pathogenic significance.

Guardado en:

Detalles Bibliográficos
Autores principales:	Tianyun Wang, Hui Guo, Bo Xiong, Holly A.F. Stessman, Huidan Wu, Bradley P. Coe, Tychele N. Turner, Yanling Liu, Wenjing Zhao, Kendra Hoekzema, Laura Vives, Lu Xia, Meina Tang, Jianjun Ou, Biyuan Chen, Yidong Shen, Guanglei Xun, Min Long, Janice Lin, Zev N. Kronenberg, Yu Peng, Ting Bai, Honghui Li, Xiaoyan Ke, Zhengmao Hu, Jingping Zhao, Xiaobing Zou, Kun Xia, Evan E. Eichler
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e8317021f8e34afa82626d911d2284db
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:e8317021f8e34afa82626d911d2284db
record_format	dspace
spelling	oai:doaj.org-article:e8317021f8e34afa82626d911d2284db2021-12-02T15:35:41ZDe novo genic mutations among a Chinese autism spectrum disorder cohort10.1038/ncomms133162041-1723https://doaj.org/article/e8317021f8e34afa82626d911d2284db2016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13316https://doaj.org/toc/2041-1723Recurrent sporadic mutations are important risk factors for autism spectrum disorders (ASDs) but have been primarily investigated in European cohorts. Here, Eichler, Xia and colleagues analyse risk genes in a large Chinese ASD cohort and find novel recurrences of potential pathogenic significance.Tianyun WangHui GuoBo XiongHolly A.F. StessmanHuidan WuBradley P. CoeTychele N. TurnerYanling LiuWenjing ZhaoKendra HoekzemaLaura VivesLu XiaMeina TangJianjun OuBiyuan ChenYidong ShenGuanglei XunMin LongJanice LinZev N. KronenbergYu PengTing BaiHonghui LiXiaoyan KeZhengmao HuJingping ZhaoXiaobing ZouKun XiaEvan E. EichlerNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tianyun Wang Hui Guo Bo Xiong Holly A.F. Stessman Huidan Wu Bradley P. Coe Tychele N. Turner Yanling Liu Wenjing Zhao Kendra Hoekzema Laura Vives Lu Xia Meina Tang Jianjun Ou Biyuan Chen Yidong Shen Guanglei Xun Min Long Janice Lin Zev N. Kronenberg Yu Peng Ting Bai Honghui Li Xiaoyan Ke Zhengmao Hu Jingping Zhao Xiaobing Zou Kun Xia Evan E. Eichler De novo genic mutations among a Chinese autism spectrum disorder cohort
description	Recurrent sporadic mutations are important risk factors for autism spectrum disorders (ASDs) but have been primarily investigated in European cohorts. Here, Eichler, Xia and colleagues analyse risk genes in a large Chinese ASD cohort and find novel recurrences of potential pathogenic significance.
format	article
author	Tianyun Wang Hui Guo Bo Xiong Holly A.F. Stessman Huidan Wu Bradley P. Coe Tychele N. Turner Yanling Liu Wenjing Zhao Kendra Hoekzema Laura Vives Lu Xia Meina Tang Jianjun Ou Biyuan Chen Yidong Shen Guanglei Xun Min Long Janice Lin Zev N. Kronenberg Yu Peng Ting Bai Honghui Li Xiaoyan Ke Zhengmao Hu Jingping Zhao Xiaobing Zou Kun Xia Evan E. Eichler
author_facet	Tianyun Wang Hui Guo Bo Xiong Holly A.F. Stessman Huidan Wu Bradley P. Coe Tychele N. Turner Yanling Liu Wenjing Zhao Kendra Hoekzema Laura Vives Lu Xia Meina Tang Jianjun Ou Biyuan Chen Yidong Shen Guanglei Xun Min Long Janice Lin Zev N. Kronenberg Yu Peng Ting Bai Honghui Li Xiaoyan Ke Zhengmao Hu Jingping Zhao Xiaobing Zou Kun Xia Evan E. Eichler
author_sort	Tianyun Wang
title	De novo genic mutations among a Chinese autism spectrum disorder cohort
title_short	De novo genic mutations among a Chinese autism spectrum disorder cohort
title_full	De novo genic mutations among a Chinese autism spectrum disorder cohort
title_fullStr	De novo genic mutations among a Chinese autism spectrum disorder cohort
title_full_unstemmed	De novo genic mutations among a Chinese autism spectrum disorder cohort
title_sort	de novo genic mutations among a chinese autism spectrum disorder cohort
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/e8317021f8e34afa82626d911d2284db
work_keys_str_mv	AT tianyunwang denovogenicmutationsamongachineseautismspectrumdisordercohort AT huiguo denovogenicmutationsamongachineseautismspectrumdisordercohort AT boxiong denovogenicmutationsamongachineseautismspectrumdisordercohort AT hollyafstessman denovogenicmutationsamongachineseautismspectrumdisordercohort AT huidanwu denovogenicmutationsamongachineseautismspectrumdisordercohort AT bradleypcoe denovogenicmutationsamongachineseautismspectrumdisordercohort AT tychelenturner denovogenicmutationsamongachineseautismspectrumdisordercohort AT yanlingliu denovogenicmutationsamongachineseautismspectrumdisordercohort AT wenjingzhao denovogenicmutationsamongachineseautismspectrumdisordercohort AT kendrahoekzema denovogenicmutationsamongachineseautismspectrumdisordercohort AT lauravives denovogenicmutationsamongachineseautismspectrumdisordercohort AT luxia denovogenicmutationsamongachineseautismspectrumdisordercohort AT meinatang denovogenicmutationsamongachineseautismspectrumdisordercohort AT jianjunou denovogenicmutationsamongachineseautismspectrumdisordercohort AT biyuanchen denovogenicmutationsamongachineseautismspectrumdisordercohort AT yidongshen denovogenicmutationsamongachineseautismspectrumdisordercohort AT guangleixun denovogenicmutationsamongachineseautismspectrumdisordercohort AT minlong denovogenicmutationsamongachineseautismspectrumdisordercohort AT janicelin denovogenicmutationsamongachineseautismspectrumdisordercohort AT zevnkronenberg denovogenicmutationsamongachineseautismspectrumdisordercohort AT yupeng denovogenicmutationsamongachineseautismspectrumdisordercohort AT tingbai denovogenicmutationsamongachineseautismspectrumdisordercohort AT honghuili denovogenicmutationsamongachineseautismspectrumdisordercohort AT xiaoyanke denovogenicmutationsamongachineseautismspectrumdisordercohort AT zhengmaohu denovogenicmutationsamongachineseautismspectrumdisordercohort AT jingpingzhao denovogenicmutationsamongachineseautismspectrumdisordercohort AT xiaobingzou denovogenicmutationsamongachineseautismspectrumdisordercohort AT kunxia denovogenicmutationsamongachineseautismspectrumdisordercohort AT evaneeichler denovogenicmutationsamongachineseautismspectrumdisordercohort
_version_	1718386506979082240

De novo genic mutations among a Chinese autism spectrum disorder cohort

Ejemplares similares