A Case Report of Tuberculosis with Extrapulmonary Manifestations

BACKGROUND AND OBJECTIVE: Mycobacterium tuberculosis affects millions of people in the world and Iran is one of the endemic areas. This disease has a wide range of manifestations, which is pulmonary in 80 – 85% of cases and extrapulmonary in 15 – 20% of cases. The most notable extrapulmonary infecti...

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Autores principales:	S Gazeran, M Emami, F Zemorshidi
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2019
Materias:	mycobacterium tuberculosis extrapulmonary psoas abscess spondylitis Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/e836b42a8a654a15992d359dd95cc4b5
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spelling	oai:doaj.org-article:e836b42a8a654a15992d359dd95cc4b52021-11-10T08:30:37ZA Case Report of Tuberculosis with Extrapulmonary Manifestations1561-41072251-7170https://doaj.org/article/e836b42a8a654a15992d359dd95cc4b52019-12-01T00:00:00Zhttp://jbums.org/article-1-8656-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170BACKGROUND AND OBJECTIVE: Mycobacterium tuberculosis affects millions of people in the world and Iran is one of the endemic areas. This disease has a wide range of manifestations, which is pulmonary in 80 – 85% of cases and extrapulmonary in 15 – 20% of cases. The most notable extrapulmonary infection sites are lymph nodes, pleura, genitourinary system and digestive system. Considering the prevalence of tuberculosis in Iran, familiarity with the uncommon manifestations of this infection seems to be essential for timely diagnosis and treatment. Therefore, a rare extrapulmonary manifestation of tuberculosis is reported here. CASE REPORT: The patient was a 64 – year – old woman who was hospitalized due to fever, icterus, decreased consciousness and progressive asymmetrical weakness of the limbs. Symptoms of focal neurologic deficits and heart murmurs were found in examinations. During the tests, including brain and spinal imaging, cerebrospinal fluid analysis, computed tomography of the abdomen and pelvis, and echocardiography, extrapulmonary tuberculosis (cerebral abscess, spondylitis, liver and spleen abscess, psoas muscle abscess, and possible endocarditis) was confirmed. Four-drug regimen including isoniazid, rifampin, ethambutol, and pyrazinamide with vitamin B6 was started for two months, and two-drug regimen continued for 10 months. At the end of the course of treatment, the patient was able to walk with the cane in good general condition. CONCLUSION: Considering the reported case, paying attention to some of the more uncommon manifestations of the disease can prevent mortality and disability.S GazeranM EmamiF ZemorshidiBabol University of Medical Sciencesarticlemycobacterium tuberculosisextrapulmonarypsoas abscessspondylitisMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 21, Iss 1, Pp 378-382 (2019)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	mycobacterium tuberculosis extrapulmonary psoas abscess spondylitis Medicine R Medicine (General) R5-920
spellingShingle	mycobacterium tuberculosis extrapulmonary psoas abscess spondylitis Medicine R Medicine (General) R5-920 S Gazeran M Emami F Zemorshidi A Case Report of Tuberculosis with Extrapulmonary Manifestations
description	BACKGROUND AND OBJECTIVE: Mycobacterium tuberculosis affects millions of people in the world and Iran is one of the endemic areas. This disease has a wide range of manifestations, which is pulmonary in 80 – 85% of cases and extrapulmonary in 15 – 20% of cases. The most notable extrapulmonary infection sites are lymph nodes, pleura, genitourinary system and digestive system. Considering the prevalence of tuberculosis in Iran, familiarity with the uncommon manifestations of this infection seems to be essential for timely diagnosis and treatment. Therefore, a rare extrapulmonary manifestation of tuberculosis is reported here. CASE REPORT: The patient was a 64 – year – old woman who was hospitalized due to fever, icterus, decreased consciousness and progressive asymmetrical weakness of the limbs. Symptoms of focal neurologic deficits and heart murmurs were found in examinations. During the tests, including brain and spinal imaging, cerebrospinal fluid analysis, computed tomography of the abdomen and pelvis, and echocardiography, extrapulmonary tuberculosis (cerebral abscess, spondylitis, liver and spleen abscess, psoas muscle abscess, and possible endocarditis) was confirmed. Four-drug regimen including isoniazid, rifampin, ethambutol, and pyrazinamide with vitamin B6 was started for two months, and two-drug regimen continued for 10 months. At the end of the course of treatment, the patient was able to walk with the cane in good general condition. CONCLUSION: Considering the reported case, paying attention to some of the more uncommon manifestations of the disease can prevent mortality and disability.
format	article
author	S Gazeran M Emami F Zemorshidi
author_facet	S Gazeran M Emami F Zemorshidi
author_sort	S Gazeran
title	A Case Report of Tuberculosis with Extrapulmonary Manifestations
title_short	A Case Report of Tuberculosis with Extrapulmonary Manifestations
title_full	A Case Report of Tuberculosis with Extrapulmonary Manifestations
title_fullStr	A Case Report of Tuberculosis with Extrapulmonary Manifestations
title_full_unstemmed	A Case Report of Tuberculosis with Extrapulmonary Manifestations
title_sort	case report of tuberculosis with extrapulmonary manifestations
publisher	Babol University of Medical Sciences
publishDate	2019
url	https://doaj.org/article/e836b42a8a654a15992d359dd95cc4b5
work_keys_str_mv	AT sgazeran acasereportoftuberculosiswithextrapulmonarymanifestations AT memami acasereportoftuberculosiswithextrapulmonarymanifestations AT fzemorshidi acasereportoftuberculosiswithextrapulmonarymanifestations AT sgazeran casereportoftuberculosiswithextrapulmonarymanifestations AT memami casereportoftuberculosiswithextrapulmonarymanifestations AT fzemorshidi casereportoftuberculosiswithextrapulmonarymanifestations
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A Case Report of Tuberculosis with Extrapulmonary Manifestations

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