Epigenome-wide association meta-analysis of DNA methylation with coffee and tea consumption

While coffee and tea consumption has been associated with risk of diseases, their mechanisms of action remain elusive. Here the authors present a large EWAS on coffee and tea consumption in cohorts of European and African-American ancestries, finding that coffee consumption is associated with differ...

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Autores principales:	Irma Karabegović, Eliana Portilla-Fernandez, Yang Li, Jiantao Ma, Silvana C. E. Maas, Daokun Sun, Emily A. Hu, Brigitte Kühnel, Yan Zhang, Srikant Ambatipudi, Giovanni Fiorito, Jian Huang, Juan E. Castillo-Fernandez, Kerri L. Wiggins, Niek de Klein, Sara Grioni, Brenton R. Swenson, Silvia Polidoro, Jorien L. Treur, Cyrille Cuenin, Pei-Chien Tsai, Ricardo Costeira, Veronique Chajes, Kim Braun, Niek Verweij, Anja Kretschmer, Lude Franke, Joyce B. J. van Meurs, André G. Uitterlinden, Robert J. de Knegt, M. Arfan Ikram, Abbas Dehghan, Annette Peters, Ben Schöttker, Sina A. Gharib, Nona Sotoodehnia, Jordana T. Bell, Paul Elliott, Paolo Vineis, Caroline Relton, Zdenko Herceg, Hermann Brenner, Melanie Waldenberger, Casey M. Rebholz, Trudy Voortman, Qiuwei Pan, Myriam Fornage, Daniel Levy, Manfred Kayser, Mohsen Ghanbari
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e843a6cca5f04b56a0da0b8c84340c1a
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spelling	oai:doaj.org-article:e843a6cca5f04b56a0da0b8c84340c1a2021-12-02T15:55:07ZEpigenome-wide association meta-analysis of DNA methylation with coffee and tea consumption10.1038/s41467-021-22752-62041-1723https://doaj.org/article/e843a6cca5f04b56a0da0b8c84340c1a2021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22752-6https://doaj.org/toc/2041-1723While coffee and tea consumption has been associated with risk of diseases, their mechanisms of action remain elusive. Here the authors present a large EWAS on coffee and tea consumption in cohorts of European and African-American ancestries, finding that coffee consumption is associated with differential DNA methylation levels at multiple CpGs.Irma KarabegovićEliana Portilla-FernandezYang LiJiantao MaSilvana C. E. MaasDaokun SunEmily A. HuBrigitte KühnelYan ZhangSrikant AmbatipudiGiovanni FioritoJian HuangJuan E. Castillo-FernandezKerri L. WigginsNiek de KleinSara GrioniBrenton R. SwensonSilvia PolidoroJorien L. TreurCyrille CueninPei-Chien TsaiRicardo CosteiraVeronique ChajesKim BraunNiek VerweijAnja KretschmerLude FrankeJoyce B. J. van MeursAndré G. UitterlindenRobert J. de KnegtM. Arfan IkramAbbas DehghanAnnette PetersBen SchöttkerSina A. GharibNona SotoodehniaJordana T. BellPaul ElliottPaolo VineisCaroline ReltonZdenko HercegHermann BrennerMelanie WaldenbergerCasey M. RebholzTrudy VoortmanQiuwei PanMyriam FornageDaniel LevyManfred KayserMohsen GhanbariNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Irma Karabegović Eliana Portilla-Fernandez Yang Li Jiantao Ma Silvana C. E. Maas Daokun Sun Emily A. Hu Brigitte Kühnel Yan Zhang Srikant Ambatipudi Giovanni Fiorito Jian Huang Juan E. Castillo-Fernandez Kerri L. Wiggins Niek de Klein Sara Grioni Brenton R. Swenson Silvia Polidoro Jorien L. Treur Cyrille Cuenin Pei-Chien Tsai Ricardo Costeira Veronique Chajes Kim Braun Niek Verweij Anja Kretschmer Lude Franke Joyce B. J. van Meurs André G. Uitterlinden Robert J. de Knegt M. Arfan Ikram Abbas Dehghan Annette Peters Ben Schöttker Sina A. Gharib Nona Sotoodehnia Jordana T. Bell Paul Elliott Paolo Vineis Caroline Relton Zdenko Herceg Hermann Brenner Melanie Waldenberger Casey M. Rebholz Trudy Voortman Qiuwei Pan Myriam Fornage Daniel Levy Manfred Kayser Mohsen Ghanbari Epigenome-wide association meta-analysis of DNA methylation with coffee and tea consumption
description	While coffee and tea consumption has been associated with risk of diseases, their mechanisms of action remain elusive. Here the authors present a large EWAS on coffee and tea consumption in cohorts of European and African-American ancestries, finding that coffee consumption is associated with differential DNA methylation levels at multiple CpGs.
format	article
author	Irma Karabegović Eliana Portilla-Fernandez Yang Li Jiantao Ma Silvana C. E. Maas Daokun Sun Emily A. Hu Brigitte Kühnel Yan Zhang Srikant Ambatipudi Giovanni Fiorito Jian Huang Juan E. Castillo-Fernandez Kerri L. Wiggins Niek de Klein Sara Grioni Brenton R. Swenson Silvia Polidoro Jorien L. Treur Cyrille Cuenin Pei-Chien Tsai Ricardo Costeira Veronique Chajes Kim Braun Niek Verweij Anja Kretschmer Lude Franke Joyce B. J. van Meurs André G. Uitterlinden Robert J. de Knegt M. Arfan Ikram Abbas Dehghan Annette Peters Ben Schöttker Sina A. Gharib Nona Sotoodehnia Jordana T. Bell Paul Elliott Paolo Vineis Caroline Relton Zdenko Herceg Hermann Brenner Melanie Waldenberger Casey M. Rebholz Trudy Voortman Qiuwei Pan Myriam Fornage Daniel Levy Manfred Kayser Mohsen Ghanbari
author_facet	Irma Karabegović Eliana Portilla-Fernandez Yang Li Jiantao Ma Silvana C. E. Maas Daokun Sun Emily A. Hu Brigitte Kühnel Yan Zhang Srikant Ambatipudi Giovanni Fiorito Jian Huang Juan E. Castillo-Fernandez Kerri L. Wiggins Niek de Klein Sara Grioni Brenton R. Swenson Silvia Polidoro Jorien L. Treur Cyrille Cuenin Pei-Chien Tsai Ricardo Costeira Veronique Chajes Kim Braun Niek Verweij Anja Kretschmer Lude Franke Joyce B. J. van Meurs André G. Uitterlinden Robert J. de Knegt M. Arfan Ikram Abbas Dehghan Annette Peters Ben Schöttker Sina A. Gharib Nona Sotoodehnia Jordana T. Bell Paul Elliott Paolo Vineis Caroline Relton Zdenko Herceg Hermann Brenner Melanie Waldenberger Casey M. Rebholz Trudy Voortman Qiuwei Pan Myriam Fornage Daniel Levy Manfred Kayser Mohsen Ghanbari
author_sort	Irma Karabegović
title	Epigenome-wide association meta-analysis of DNA methylation with coffee and tea consumption
title_short	Epigenome-wide association meta-analysis of DNA methylation with coffee and tea consumption
title_full	Epigenome-wide association meta-analysis of DNA methylation with coffee and tea consumption
title_fullStr	Epigenome-wide association meta-analysis of DNA methylation with coffee and tea consumption
title_full_unstemmed	Epigenome-wide association meta-analysis of DNA methylation with coffee and tea consumption
title_sort	epigenome-wide association meta-analysis of dna methylation with coffee and tea consumption
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/e843a6cca5f04b56a0da0b8c84340c1a
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Epigenome-wide association meta-analysis of DNA methylation with coffee and tea consumption

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