Galanin neurons in the ventrolateral preoptic area promote sleep and heat loss in mice

Anatomical lesions of the preoptic area (POA) can cause sleep loss while electrical, chemical, or thermal stimulation of POA can induce sleep. To better understand the exact neural function of the POA, this study shows that galanin and GABA+ inhibitory neurons in the ventrolateral POA that project t...

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Autores principales:	Daniel Kroeger, Gianna Absi, Celia Gagliardi, Sathyajit S. Bandaru, Joseph C. Madara, Loris L. Ferrari, Elda Arrigoni, Heike Münzberg, Thomas E. Scammell, Clifford B. Saper, Ramalingam Vetrivelan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e84b4da88d7f473b8b512f6a39eff1b9
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spelling	oai:doaj.org-article:e84b4da88d7f473b8b512f6a39eff1b92021-12-02T14:39:09ZGalanin neurons in the ventrolateral preoptic area promote sleep and heat loss in mice10.1038/s41467-018-06590-72041-1723https://doaj.org/article/e84b4da88d7f473b8b512f6a39eff1b92018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06590-7https://doaj.org/toc/2041-1723Anatomical lesions of the preoptic area (POA) can cause sleep loss while electrical, chemical, or thermal stimulation of POA can induce sleep. To better understand the exact neural function of the POA, this study shows that galanin and GABA+ inhibitory neurons in the ventrolateral POA that project to the wake-promoting tuberomammillary nucleus promote sleep in a stimulation frequency dependent manner.Daniel KroegerGianna AbsiCelia GagliardiSathyajit S. BandaruJoseph C. MadaraLoris L. FerrariElda ArrigoniHeike MünzbergThomas E. ScammellClifford B. SaperRamalingam VetrivelanNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Daniel Kroeger Gianna Absi Celia Gagliardi Sathyajit S. Bandaru Joseph C. Madara Loris L. Ferrari Elda Arrigoni Heike Münzberg Thomas E. Scammell Clifford B. Saper Ramalingam Vetrivelan Galanin neurons in the ventrolateral preoptic area promote sleep and heat loss in mice
description	Anatomical lesions of the preoptic area (POA) can cause sleep loss while electrical, chemical, or thermal stimulation of POA can induce sleep. To better understand the exact neural function of the POA, this study shows that galanin and GABA+ inhibitory neurons in the ventrolateral POA that project to the wake-promoting tuberomammillary nucleus promote sleep in a stimulation frequency dependent manner.
format	article
author	Daniel Kroeger Gianna Absi Celia Gagliardi Sathyajit S. Bandaru Joseph C. Madara Loris L. Ferrari Elda Arrigoni Heike Münzberg Thomas E. Scammell Clifford B. Saper Ramalingam Vetrivelan
author_facet	Daniel Kroeger Gianna Absi Celia Gagliardi Sathyajit S. Bandaru Joseph C. Madara Loris L. Ferrari Elda Arrigoni Heike Münzberg Thomas E. Scammell Clifford B. Saper Ramalingam Vetrivelan
author_sort	Daniel Kroeger
title	Galanin neurons in the ventrolateral preoptic area promote sleep and heat loss in mice
title_short	Galanin neurons in the ventrolateral preoptic area promote sleep and heat loss in mice
title_full	Galanin neurons in the ventrolateral preoptic area promote sleep and heat loss in mice
title_fullStr	Galanin neurons in the ventrolateral preoptic area promote sleep and heat loss in mice
title_full_unstemmed	Galanin neurons in the ventrolateral preoptic area promote sleep and heat loss in mice
title_sort	galanin neurons in the ventrolateral preoptic area promote sleep and heat loss in mice
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/e84b4da88d7f473b8b512f6a39eff1b9
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Galanin neurons in the ventrolateral preoptic area promote sleep and heat loss in mice

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