Lin−CCR2+ hematopoietic stem and progenitor cells overcome resistance to PD-1 blockade

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Lin−CCR2+ hematopoietic stem and progenitor cells overcome resistance to PD-1 blockade

Brain tumors are difficult to treat using existing immunotherapeutic strategies. Here, the authors show that in brain tumors resistant to PD-1 blockade, HSCs expressing CCR2+ can reverse treatment resistance and sensitizes mice to immunotherapy.

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Detalles Bibliográficos
Autores principales:	Catherine T. Flores, Tyler J. Wildes, Jeffrey A. Drake, Ginger L. Moore, Bayli DiVita Dean, Rebecca S. Abraham, Duane A. Mitchell
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e858bb0fbd22476293c8ca108b30024b
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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