The nose is the best niche for detection of experimental pneumococcal colonisation in adults of all ages, using nasal wash

Abstract Previous studies have suggested that the pneumococcal niche changes from the nasopharynx to the oral cavity with age. We use an Experimental Human Pneumococcal Challenge model to investigate pneumococcal colonisation in different anatomical niches with age. Healthy adults (n = 112) were int...

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Bibliographic Details
Main Authors: Elissavet Nikolaou, Esther L. German, Annie Blizard, Ashleigh Howard, Lisa Hitchins, Tao Chen, Jim Chadwick, Sherin Pojar, Elena Mitsi, Carla Solórzano, Syba Sunny, Felicity Dunne, Jenna F. Gritzfeld, Hugh Adler, Jason Hinds, Katherine A. Gould, Jamie Rylance, Andrea M. Collins, Stephen B. Gordon, Daniela M. Ferreira
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/e86701c2f70341c0a89b2827ecb7542b
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