The metabolomics of psoriatic disease

Di Yan, Ladan Afifi, Caleb Jeon, Megha Trivedi, Hsin Wen Chang, Kristina Lee, Wilson Liao Department of Dermatology, University of California-San Francisco, San Francisco, CA, USA Abstract: Metabolomics is an emerging new “omics&rdq...

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Autores principales:	Yan D, Afifi L, Jeon C, Trivedi M, Chang HW, Lee K, Liao W
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	Metabolome Psoriasis Psoriatic arthritis Skin Urine Metabolites Dermatology RL1-803
Acceso en línea:	https://doaj.org/article/e8724ac9a9f74989a8b34e1b4f6a1544
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spelling	oai:doaj.org-article:e8724ac9a9f74989a8b34e1b4f6a15442021-12-02T01:20:44ZThe metabolomics of psoriatic disease2230-326Xhttps://doaj.org/article/e8724ac9a9f74989a8b34e1b4f6a15442017-01-01T00:00:00Zhttps://www.dovepress.com/the-metabolomics-of-psoriatic-disease-peer-reviewed-article-PTThttps://doaj.org/toc/2230-326XDi Yan, Ladan Afifi, Caleb Jeon, Megha Trivedi, Hsin Wen Chang, Kristina Lee, Wilson Liao Department of Dermatology, University of California-San Francisco, San Francisco, CA, USA Abstract: Metabolomics is an emerging new “omics” field involving the systematic analysis of the metabolites in a biologic system. These metabolites provide a molecular snapshot of cellular activity and are thus important for understanding the functional changes in metabolic pathways that drive disease. Recently, metabolomics has been used to study the local and systemic metabolic changes in psoriasis and its cardiometabolic comorbidities. Such studies have revealed novel insights into disease pathogenesis and suggest new biochemical signatures that may be used as a marker of psoriatic disease. This review will discuss common strategies in metabolomics analysis, current findings in the metabolomics of psoriasis, and emerging trends in psoriatic metabolomics. Keywords: metabolome, psoriasis, psoriatic arthritis, skin, urine, metabolitesYan DAfifi LJeon CTrivedi MChang HWLee KLiao WDove Medical PressarticleMetabolomePsoriasisPsoriatic arthritisSkinUrineMetabolitesDermatologyRL1-803ENPsoriasis: Targets and Therapy, Vol Volume 7, Pp 1-15 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Metabolome Psoriasis Psoriatic arthritis Skin Urine Metabolites Dermatology RL1-803
spellingShingle	Metabolome Psoriasis Psoriatic arthritis Skin Urine Metabolites Dermatology RL1-803 Yan D Afifi L Jeon C Trivedi M Chang HW Lee K Liao W The metabolomics of psoriatic disease
description	Di Yan, Ladan Afifi, Caleb Jeon, Megha Trivedi, Hsin Wen Chang, Kristina Lee, Wilson Liao Department of Dermatology, University of California-San Francisco, San Francisco, CA, USA Abstract: Metabolomics is an emerging new “omics” field involving the systematic analysis of the metabolites in a biologic system. These metabolites provide a molecular snapshot of cellular activity and are thus important for understanding the functional changes in metabolic pathways that drive disease. Recently, metabolomics has been used to study the local and systemic metabolic changes in psoriasis and its cardiometabolic comorbidities. Such studies have revealed novel insights into disease pathogenesis and suggest new biochemical signatures that may be used as a marker of psoriatic disease. This review will discuss common strategies in metabolomics analysis, current findings in the metabolomics of psoriasis, and emerging trends in psoriatic metabolomics. Keywords: metabolome, psoriasis, psoriatic arthritis, skin, urine, metabolites
format	article
author	Yan D Afifi L Jeon C Trivedi M Chang HW Lee K Liao W
author_facet	Yan D Afifi L Jeon C Trivedi M Chang HW Lee K Liao W
author_sort	Yan D
title	The metabolomics of psoriatic disease
title_short	The metabolomics of psoriatic disease
title_full	The metabolomics of psoriatic disease
title_fullStr	The metabolomics of psoriatic disease
title_full_unstemmed	The metabolomics of psoriatic disease
title_sort	metabolomics of psoriatic disease
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/e8724ac9a9f74989a8b34e1b4f6a1544
work_keys_str_mv	AT yand themetabolomicsofpsoriaticdisease AT afifil themetabolomicsofpsoriaticdisease AT jeonc themetabolomicsofpsoriaticdisease AT trivedim themetabolomicsofpsoriaticdisease AT changhw themetabolomicsofpsoriaticdisease AT leek themetabolomicsofpsoriaticdisease AT liaow themetabolomicsofpsoriaticdisease AT yand metabolomicsofpsoriaticdisease AT afifil metabolomicsofpsoriaticdisease AT jeonc metabolomicsofpsoriaticdisease AT trivedim metabolomicsofpsoriaticdisease AT changhw metabolomicsofpsoriaticdisease AT leek metabolomicsofpsoriaticdisease AT liaow metabolomicsofpsoriaticdisease
_version_	1718403170722381824

The metabolomics of psoriatic disease

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