Antioxidant Activities and Identification of an Active Compound from Rambutan (<i>Nephelium lappaceum</i> L.) Peel

The consumption of rambutan fruit resulted in a vast amount of peels and seeds waste. Therefore, the exploration of active compounds having beneficial effects on human health, such as antioxidants, is very lucrative. This research was aimed to isolate and to identify the active compound as an antiox...

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Autores principales:	Mistriyani Mistriyani, Sugeng Riyanto, Anjar Windarsih, Abdul Rohman
Formato:	article
Lenguaje:	EN
Publicado:	Department of Chemistry, Universitas Gadjah Mada 2020
Materias:	rambutan peel dpph metal-chelating 3,4-dihydroxybenzoic acid Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/e883e155586b49bab6a3a5c35310da71
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spelling	oai:doaj.org-article:e883e155586b49bab6a3a5c35310da712021-12-02T15:58:50ZAntioxidant Activities and Identification of an Active Compound from Rambutan (<i>Nephelium lappaceum</i> L.) Peel1411-94202460-157810.22146/ijc.50421https://doaj.org/article/e883e155586b49bab6a3a5c35310da712020-12-01T00:00:00Zhttps://jurnal.ugm.ac.id/ijc/article/view/50421https://doaj.org/toc/1411-9420https://doaj.org/toc/2460-1578The consumption of rambutan fruit resulted in a vast amount of peels and seeds waste. Therefore, the exploration of active compounds having beneficial effects on human health, such as antioxidants, is very lucrative. This research was aimed to isolate and to identify the active compound as an antioxidant from rambutan peel. The powdered rambutan peel was extracted with a maceration technique using methanol then fractionated using petroleum ether, chloroform, and ethyl acetate to get the corresponding fractions. The extract and fractions were determined for its antioxidant activities in vitro using 2,2’-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging and metal-chelating assay. The ethyl acetate fraction exhibited the highest antiradical activity with an IC50 value of 26.22 μg/mL and metal-chelating activity, accounting for 12.32%. The antioxidant activities of extract and fractions correlated with its phenolics and flavonoid contents. Identification of active compounds using FTIR, GC-MS, and NMR resulted in the chemical formula of C7H6O4, identified as 3,4-dihydroxybenzoic acid.Mistriyani MistriyaniSugeng RiyantoAnjar WindarsihAbdul RohmanDepartment of Chemistry, Universitas Gadjah Madaarticlerambutan peeldpphmetal-chelating3,4-dihydroxybenzoic acidChemistryQD1-999ENIndonesian Journal of Chemistry, Vol 21, Iss 2, Pp 259-267 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	rambutan peel dpph metal-chelating 3,4-dihydroxybenzoic acid Chemistry QD1-999
spellingShingle	rambutan peel dpph metal-chelating 3,4-dihydroxybenzoic acid Chemistry QD1-999 Mistriyani Mistriyani Sugeng Riyanto Anjar Windarsih Abdul Rohman Antioxidant Activities and Identification of an Active Compound from Rambutan (<i>Nephelium lappaceum</i> L.) Peel
description	The consumption of rambutan fruit resulted in a vast amount of peels and seeds waste. Therefore, the exploration of active compounds having beneficial effects on human health, such as antioxidants, is very lucrative. This research was aimed to isolate and to identify the active compound as an antioxidant from rambutan peel. The powdered rambutan peel was extracted with a maceration technique using methanol then fractionated using petroleum ether, chloroform, and ethyl acetate to get the corresponding fractions. The extract and fractions were determined for its antioxidant activities in vitro using 2,2’-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging and metal-chelating assay. The ethyl acetate fraction exhibited the highest antiradical activity with an IC50 value of 26.22 μg/mL and metal-chelating activity, accounting for 12.32%. The antioxidant activities of extract and fractions correlated with its phenolics and flavonoid contents. Identification of active compounds using FTIR, GC-MS, and NMR resulted in the chemical formula of C7H6O4, identified as 3,4-dihydroxybenzoic acid.
format	article
author	Mistriyani Mistriyani Sugeng Riyanto Anjar Windarsih Abdul Rohman
author_facet	Mistriyani Mistriyani Sugeng Riyanto Anjar Windarsih Abdul Rohman
author_sort	Mistriyani Mistriyani
title	Antioxidant Activities and Identification of an Active Compound from Rambutan (<i>Nephelium lappaceum</i> L.) Peel
title_short	Antioxidant Activities and Identification of an Active Compound from Rambutan (<i>Nephelium lappaceum</i> L.) Peel
title_full	Antioxidant Activities and Identification of an Active Compound from Rambutan (<i>Nephelium lappaceum</i> L.) Peel
title_fullStr	Antioxidant Activities and Identification of an Active Compound from Rambutan (<i>Nephelium lappaceum</i> L.) Peel
title_full_unstemmed	Antioxidant Activities and Identification of an Active Compound from Rambutan (<i>Nephelium lappaceum</i> L.) Peel
title_sort	antioxidant activities and identification of an active compound from rambutan (<i>nephelium lappaceum</i> l.) peel
publisher	Department of Chemistry, Universitas Gadjah Mada
publishDate	2020
url	https://doaj.org/article/e883e155586b49bab6a3a5c35310da71
work_keys_str_mv	AT mistriyanimistriyani antioxidantactivitiesandidentificationofanactivecompoundfromrambutaninepheliumlappaceumilpeel AT sugengriyanto antioxidantactivitiesandidentificationofanactivecompoundfromrambutaninepheliumlappaceumilpeel AT anjarwindarsih antioxidantactivitiesandidentificationofanactivecompoundfromrambutaninepheliumlappaceumilpeel AT abdulrohman antioxidantactivitiesandidentificationofanactivecompoundfromrambutaninepheliumlappaceumilpeel
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Antioxidant Activities and Identification of an Active Compound from Rambutan (<i>Nephelium lappaceum</i> L.) Peel

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