The careg element reveals a common regulation of regeneration in the zebrafish myocardium and fin

Common mechanisms underlie organ regeneration, but it is unclear if the same regulatory elements are activated in distinct cells, such as cardiomyocytes and fibroblasts. Here, the authors identify actgfa upstream sequence, called careg, induced by TGFb/Activin during zebrafish heart and fin regenera...

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Autores principales: Catherine Pfefferli, Anna Jaźwińska
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/e8851133784d4c29ba355c161c250fa1
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Sumario:Common mechanisms underlie organ regeneration, but it is unclear if the same regulatory elements are activated in distinct cells, such as cardiomyocytes and fibroblasts. Here, the authors identify actgfa upstream sequence, called careg, induced by TGFb/Activin during zebrafish heart and fin regeneration.