Association of plasminogen activator inhibitor-type 1 (-675 4G/5G) polymorphism with pre-eclampsia: systematic review.
<h4>Background and aims</h4>Excessive generation of plasminogen activator inhibitor-type 1 (PAI-1) is implicated in the pathogenesis of pre-eclampsia and related conditions. The PAI-1 (-675 4G/5G) promoter polymorphism (rs1799889) affects transcriptional activity and is a putative geneti...
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Main Authors: | Jessie A Morgan, Sarah Bombell, William McGuire |
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Format: | article |
Language: | EN |
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Public Library of Science (PLoS)
2013
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Online Access: | https://doaj.org/article/e88d1687f02b41c38a973a5f04718ee1 |
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