Rapid and simple CZE-UV method for quality control of B1 and B6 vitamins in drugs and dietary supplements

The application of hydrodynamically closed capillary zone electrophoresis combined with convenient ultraviolet (UV) detection allows fast, simple, environmentally friendly and cost-effective analysis of ions or ionisable molecules. This technique has been used to determine two selected B vitamins (t...

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Autores principales:	Matuskova M., Cizmarova I., Chalova P., Mikus P., Piestansky J.
Formato:	article
Lenguaje:	EN
Publicado:	Sciendo 2021
Materias:	capillary zone electrophoresis hydrodynamically closed system ultraviolet detection thiamine pyridoxine quality control Therapeutics. Pharmacology RM1-950
Acceso en línea:	https://doaj.org/article/e88d76fecf024fd1a385b08e96a35ff1
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spelling	oai:doaj.org-article:e88d76fecf024fd1a385b08e96a35ff12021-12-05T14:11:05ZRapid and simple CZE-UV method for quality control of B1 and B6 vitamins in drugs and dietary supplements2453-672510.2478/afpuc-2021-0002https://doaj.org/article/e88d76fecf024fd1a385b08e96a35ff12021-07-01T00:00:00Zhttps://doi.org/10.2478/afpuc-2021-0002https://doaj.org/toc/2453-6725The application of hydrodynamically closed capillary zone electrophoresis combined with convenient ultraviolet (UV) detection allows fast, simple, environmentally friendly and cost-effective analysis of ions or ionisable molecules. This technique has been used to determine two selected B vitamins (thiamine, pyridoxine) in various drug formulations. The developed method was characterised by excellent validation parameters, such as linearity, precision, accuracy, limit of detection and limit of quantification. The total time of analysis was lower than 13.5 min. The results indicate that the method is suitable for implementation in routine quality control of selected B vitamins in pharmaceutical and food samples.Matuskova M.Cizmarova I.Chalova P.Mikus P.Piestansky J.Sciendoarticlecapillary zone electrophoresishydrodynamically closed systemultraviolet detectionthiaminepyridoxinequality controlTherapeutics. PharmacologyRM1-950ENEuropean Pharmaceutical Journal, Vol 68, Iss 1, Pp 59-62 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	capillary zone electrophoresis hydrodynamically closed system ultraviolet detection thiamine pyridoxine quality control Therapeutics. Pharmacology RM1-950
spellingShingle	capillary zone electrophoresis hydrodynamically closed system ultraviolet detection thiamine pyridoxine quality control Therapeutics. Pharmacology RM1-950 Matuskova M. Cizmarova I. Chalova P. Mikus P. Piestansky J. Rapid and simple CZE-UV method for quality control of B1 and B6 vitamins in drugs and dietary supplements
description	The application of hydrodynamically closed capillary zone electrophoresis combined with convenient ultraviolet (UV) detection allows fast, simple, environmentally friendly and cost-effective analysis of ions or ionisable molecules. This technique has been used to determine two selected B vitamins (thiamine, pyridoxine) in various drug formulations. The developed method was characterised by excellent validation parameters, such as linearity, precision, accuracy, limit of detection and limit of quantification. The total time of analysis was lower than 13.5 min. The results indicate that the method is suitable for implementation in routine quality control of selected B vitamins in pharmaceutical and food samples.
format	article
author	Matuskova M. Cizmarova I. Chalova P. Mikus P. Piestansky J.
author_facet	Matuskova M. Cizmarova I. Chalova P. Mikus P. Piestansky J.
author_sort	Matuskova M.
title	Rapid and simple CZE-UV method for quality control of B1 and B6 vitamins in drugs and dietary supplements
title_short	Rapid and simple CZE-UV method for quality control of B1 and B6 vitamins in drugs and dietary supplements
title_full	Rapid and simple CZE-UV method for quality control of B1 and B6 vitamins in drugs and dietary supplements
title_fullStr	Rapid and simple CZE-UV method for quality control of B1 and B6 vitamins in drugs and dietary supplements
title_full_unstemmed	Rapid and simple CZE-UV method for quality control of B1 and B6 vitamins in drugs and dietary supplements
title_sort	rapid and simple cze-uv method for quality control of b1 and b6 vitamins in drugs and dietary supplements
publisher	Sciendo
publishDate	2021
url	https://doaj.org/article/e88d76fecf024fd1a385b08e96a35ff1
work_keys_str_mv	AT matuskovam rapidandsimpleczeuvmethodforqualitycontrolofb1andb6vitaminsindrugsanddietarysupplements AT cizmarovai rapidandsimpleczeuvmethodforqualitycontrolofb1andb6vitaminsindrugsanddietarysupplements AT chalovap rapidandsimpleczeuvmethodforqualitycontrolofb1andb6vitaminsindrugsanddietarysupplements AT mikusp rapidandsimpleczeuvmethodforqualitycontrolofb1andb6vitaminsindrugsanddietarysupplements AT piestanskyj rapidandsimpleczeuvmethodforqualitycontrolofb1andb6vitaminsindrugsanddietarysupplements
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Rapid and simple CZE-UV method for quality control of B1 and B6 vitamins in drugs and dietary supplements

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